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Related Concept Videos

Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

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Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
42
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

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Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
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Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

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Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
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Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

529
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
529
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

36
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
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Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

149
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
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Related Experiment Video

Updated: Sep 22, 2025

Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine
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Implementation of a Synergistic, Complementary Pharmacy Practice Model for an Advanced Heart Failure/Heart Transplant

Luke Gormley1, Caitlin Mullins2, Lynne M Sylvia2

  • 1Department of Pharmacy, Allegheny General Hospital, Pittsburgh, PA, USA.

Journal of Pharmacy Practice
|May 23, 2022
PubMed
Summary

A specialized pharmacy team improved medication access, education, and care transitions for advanced heart failure (HF) and transplant patients, enhancing medication safety and increasing outpatient prescription revenue.

Keywords:
heart failureheart transplantationpharmacy practice modeltransitions of care

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Area of Science:

  • Pharmacy Practice
  • Cardiology
  • Transplant Medicine

Background:

  • Advanced heart failure (HF) and transplant patients face challenges with medication access, education, and care transitions (ToC).
  • A dedicated pharmacy practice model was developed to address these critical gaps in patient care.

Purpose of the Study:

  • To describe the activities of a four-member pharmacy team (3 pharmacists, 1 specialty technician) in an Advanced HF/Transplant program.
  • To evaluate the impact of this pharmacy practice model on medication access, education, and ToC for high-risk patients.

Main Methods:

  • Prospective data collection in 2020 for 284 admissions of advanced HF/transplant patients and ambulatory HF clinic patients.
  • Interventions included daily medication reconciliation, e-prescribing, patient consultation, and telephone callbacks.
  • Metrics quantified included medication access, education completion, ToC points, and outpatient prescription volume and revenue.

Main Results:

  • 97% of patients received standardized discharge medication education.
  • 100% of newly transplanted or LVAD patients had medication access on discharge and received follow-up consultation within 48 hours.
  • Outpatient prescription volume increased by 42%, with a 157% net revenue increase.

Conclusions:

  • An integrated pharmacy practice model significantly improved medication access, education, and ToC for advanced HF/transplant patients.
  • This model enhanced medication safety through coordinated care across inpatient, outpatient, and specialty settings.
  • Collaboration between pharmacists and technicians is crucial for optimizing care for high-risk patient populations.