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Biaxial Mechanical Characterizations of Atrioventricular Heart Valves
Published on: April 9, 2019
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Trifecta versus Perimount Magna Ease aortic valves: Failure mechanisms
Ryo Suzuki1, Toshiro Ito1, Masato Suzuki1
1Department of Cardiovascular Surgery, 157484Hokkaido Ohno Memorial Hospital, Hokkaido, Japan.
Asian Cardiovascular & Thoracic Annals
|May 23, 2022
Summary
Early Trifecta bioprosthesis failure is more common than with the Carpentier-Edwards Perimount Magna Ease valve. Prosthetic valve aortic regurgitation and structural valve deterioration drive Trifecta valve failure, necessitating reoperation.
Area of Science:
- Cardiovascular Surgery
- Biomaterials Science
- Medical Device Engineering
Background:
- Increasing reports of early Trifecta bioprosthesis failure.
- Need to compare hemodynamic performance of Trifecta and Carpentier-Edwards Perimount Magna Ease valves.
Purpose of the Study:
- Determine the failure mechanism of externally mounted pericardial Trifecta bioprosthesis.
- Compare early hemodynamic performance and failure rates between Trifecta and Carpentier-Edwards Perimount Magna Ease valves.
Main Methods:
- Retrospective study of 270 patients undergoing aortic valve replacement (2014-2021).
- Compared Trifecta (N=137) and Carpentier-Edwards Perimount Magna Ease (N=133) valve patients.
- Mean follow-up of 48.0 months.
Main Results:
- Higher incidence of major aortic regurgitation in Trifecta valves (6.3% vs. 0%, P<0.009).
- Structural valve deterioration occurred in 33% of Trifecta failures, leading to redo aortic valve replacement.
- Significantly lower freedom from redo aortic valve replacement due to structural valve deterioration at 5 years for Trifecta (89.4% vs. 100%, P=0.003).
- Prosthetic valve aortic regurgitation was a sole contributor to redo aortic valve replacement (HR: 2.38).
Conclusions:
- Trifecta valves exhibit significantly more early failures compared to Carpentier-Edwards Perimount Magna Ease valves.
- Prosthetic valve aortic regurgitation and calcific structural valve deterioration synergistically contribute to Trifecta valve failure.
- Trifecta valves demonstrated a reasonable mean transprosthetic pressure gradient over time.
Keywords:
Magna easeTrifectaaortic prosthetic valve regurgitationaortic valve replacementreoperationstructural valve deteriorationMore Related Videos
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