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Finger millet-based muffin decreases insulin response in individuals with prediabetes in a randomised controlled

Ameerah Almaski1,2, Shelly Coe2, Helen Lightowler2

  • 1Department of Nutrition and Food Science, Taibah University, Universities Road, PO Box: 344, KSA, Medina, Saudi Arabia.

The British Journal of Nutrition
|May 23, 2022
PubMed

Insights

Finger millet muffins, rich in polyphenols, significantly reduced blood glucose and insulin response in individuals with prediabetes compared to wheat muffins. This suggests millet

Area of Science:

  • Nutritional Science
  • Human Physiology
  • Dietary Interventions

Background:

  • Millet is a grain rich in polyphenols and antioxidants.
  • These bioactive compounds can influence blood glucose response.
  • Dietary choices impact glycaemic control, particularly in prediabetes.

Purpose of the Study:

  • To compare the effects of finger millet and wheat muffins on glycaemic response (GR), insulin response (IR), gastric emptying (GE), and satiety.
  • To evaluate these effects in both healthy individuals and those with prediabetes.
  • To investigate the potential of millet in managing prediabetes.

Main Methods:

  • Single-blind randomised controlled crossover trial.
  • Recruited 15 healthy and 14 prediabetic individuals.
  • Measured GR, IR, GE, and satiety before and after muffin consumption.
  • Utilised mixed method ANOVA for data analysis.

Main Results:

  • Millet muffins significantly decreased the GR peak and IR incremental area under the curve (iAUC) in prediabetic participants compared to wheat muffins.
  • A significant interaction between participants and muffins was observed for IR iAUC and GE ascension time.
  • No significant effect of muffins on satiety was found across participant groups.

Conclusions:

  • Polyphenol and fibre-rich finger millet shows potential for managing prediabetes.
  • Millet consumption may positively influence glycaemic and insulin responses.
  • Further research into millet-based dietary strategies for metabolic health is warranted.
Keywords:
Finger milletGastric emptyingGlycaemic responseInsulinaemic responsePrediabetes

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