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An indanone-based fluorescent probe for detection and imaging of Cys/Hcy in living cells
Shuwei Zhang1, Wenyi Liao1, Xuewen Wang2
1School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China.
Abstract:
Effective detection of Cys and Hcy plays an important role in the diagnosis of diseases. In this work, a novel indanone-based fluorescent probe INIAc-CN for sensitively and effectively detecting Cys and Hcy was developed. The probe exhibited weak fluorescence, but obvious fluorescent enhancement after reacted with Cys/Hcy. Moreover, the good anti-interference and low cytotoxicity of the probe made it successfully applied for monitoring Cys and Hcy of in living cells.
