Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Classification of Epithelial Tissues: Overview01:22

Classification of Epithelial Tissues: Overview

15.7K
Epithelial tissues are classified according to the shape of the cells and the number of cell layers formed. Cell shapes can be squamous (flattened and thin), cuboidal (square-like, as wide as it is tall), or columnar (rectangular, taller than it is wide). Additionally, the nucleus shape helps identify the type of epithelial cells. Squamous cells have flattened disc-shaped nuclei, cuboidal cells have spherical nuclei, and columnar cells have elongated nuclei.
Based on the number of cell layers,...
15.7K
Cadherins in Tissue Organization01:19

Cadherins in Tissue Organization

3.2K
The cadherins are a superfamily of cell adhesion molecules comprising over 180 variants, with specific tissues expressing a particular combination of cadherin types. Cadherins generally exhibit homophilic binding; i.e., cadherins on one cell bind to cadherins of the same or closely related type on another cell. Thus, cells of the same type have a specific affinity to bind to each other and sort themselves into clusters to form tissues.
Cell Sorting During Development
Cell sorting plays an...
3.2K
Classification of Epithelial Tissues: Glandular Epithelium01:20

Classification of Epithelial Tissues: Glandular Epithelium

9.9K
The glandular epithelium is made of one or more epithelial cells modified to synthesize and secrete chemical substances. Glandular epithelia can be classified based on cell number. Unicellular glands have individual secretory cells scattered across the epithelial monolayer. In contrast, multicellular glands consist of a hollow tubular duct attached to the cluster of secretory cells located in the deep pockets.
Multicellular glands are formed during early development when epithelial budding...
9.9K
Epithelial Tissues and Their Functions01:23

Epithelial Tissues and Their Functions

25.5K
Epithelial tissues are large sheets of cells covering all of the surfaces of the body. These surfaces can be internal or external, for example, skin, airways, the digestive tract, the urinary system, and the reproductive system. Hollow organs and body cavities that do not connect to the body's exterior, including blood vessels and serous membranes, are lined by epithelial tissue known as the endothelium.
Epithelial tissues provide the body's first line of protection from physical,...
25.5K
Morphogenesis02:19

Morphogenesis

28.9K
Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
28.9K
Role of Ephrin-Eph Signalling in Intestinal Stem Cell Renewal01:22

Role of Ephrin-Eph Signalling in Intestinal Stem Cell Renewal

2.3K
Erythropoietin-producing hepatocellular carcinoma receptor (Eph) and its ligand, Eph receptor-interacting protein (Ephrin) were first discovered in the human carcinoma cell line, hence the name. Ephrin-Eph interaction guides cells to reach their appropriate location in adult tissues. They also play an essential role in the immune system by helping in immune cell migration, adhesion, and activation. Based on their structure and function, Eph is divided into two classes — EphA and EphB.
2.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advancing mechanobiology from single molecules to complex cellular systems.

Nature nanotechnology·2026
Same author

MorphoGrad: A MATLAB toolbox for simulating steady-state morphogen gradients under cell-to-cell variability.

STAR protocols·2026
Same author

Coordination of nephrogenesis with branching of the urinary collecting system, the vasculature and the nervous system.

Current topics in developmental biology·2025
Same author

The first two blastomeres contribute unequally to the human embryo.

Cell·2024
Same author

Publisher Correction: SimuCell3D: three-dimensional simulation of tissue mechanics with cell polarization.

Nature computational science·2024
Same author

SimuCell3D: three-dimensional simulation of tissue mechanics with cell polarization.

Nature computational science·2024
Same journal

Temporal trajectories underlying adult neuronal diversity.

Current opinion in genetics & development·2026
Same journal

Transcription regulation of cell fate plasticity - from embryonic development to tissue regeneration.

Current opinion in genetics & development·2026
Same journal

Shared molecular and cellular programs during regeneration of glandular epithelia.

Current opinion in genetics & development·2026
Same journal

Lineage tracing in human cortical development.

Current opinion in genetics & development·2026
Same journal

Cis-regulatory strategies in developmental patterning.

Current opinion in genetics & development·2026
Same journal

GABAergic neuron fate specification and lineage allocation: from development to disorder.

Current opinion in genetics & development·2026
See all related articles

Related Experiment Video

Updated: Sep 22, 2025

Engineering Three-dimensional Epithelial Tissues Embedded within Extracellular Matrix
08:49

Engineering Three-dimensional Epithelial Tissues Embedded within Extracellular Matrix

Published on: July 10, 2016

7.7K

Relationship between epithelial organization and morphogen interpretation.

Dagmar Iber1, Roman Vetter1

  • 1Department of Biosystems Science and Engineering, ETH Zürich, Mattenstrasse 26, 4058 Basel, Switzerland; Swiss Institute of Bioinformatics, Mattenstrasse 26, 4058 Basel, Switzerland.

Current Opinion in Genetics & Development
|May 23, 2022
PubMed
Summary
This summary is machine-generated.

Developmental biology achieves consistent outcomes despite genetic variations. Chemical gradients and epithelial cell shapes may be key linked mechanisms driving this precise development.

More Related Videos

Mucociliary Epithelial Organoids from Xenopus Embryonic Cells: Generation, Culture and High-Resolution Live Imaging
07:44

Mucociliary Epithelial Organoids from Xenopus Embryonic Cells: Generation, Culture and High-Resolution Live Imaging

Published on: July 28, 2020

4.9K
Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages
08:25

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages

Published on: June 2, 2020

9.6K

Related Experiment Videos

Last Updated: Sep 22, 2025

Engineering Three-dimensional Epithelial Tissues Embedded within Extracellular Matrix
08:49

Engineering Three-dimensional Epithelial Tissues Embedded within Extracellular Matrix

Published on: July 10, 2016

7.7K
Mucociliary Epithelial Organoids from Xenopus Embryonic Cells: Generation, Culture and High-Resolution Live Imaging
07:44

Mucociliary Epithelial Organoids from Xenopus Embryonic Cells: Generation, Culture and High-Resolution Live Imaging

Published on: July 28, 2020

4.9K
Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages
08:25

Imaging and Analysis of Tissue Orientation and Growth Dynamics in the Developing Drosophila Epithelia During Pupal Stages

Published on: June 2, 2020

9.6K

Area of Science:

  • Developmental biology
  • Cell biology
  • Morphogenesis

Background:

  • Biological development exhibits remarkable consistency despite inherent molecular noise and individual genetic variations.
  • Ensuring developmental precision and robustness has been a central focus of biological research for decades.

Purpose of the Study:

  • To review recent insights into the mechanisms underlying precise development.
  • To explore the potential link between chemical gradients and epithelial cell shapes in epithelial morphogenesis.

Main Methods:

  • Review of recent quantitative data on chemical gradients.
  • Analysis of studies on epithelial cell shape dynamics.
  • Synthesis of findings to propose a link between these factors.

Main Results:

  • Quantification of chemical gradients offers new perspectives on developmental precision.
  • Epithelial cell shape dynamics provide insights into robust developmental processes.
  • A potential mechanistic link between chemical gradients and cell shape in morphogenesis is proposed.

Conclusions:

  • Chemical gradients and epithelial cell shapes are likely interconnected factors in ensuring developmental robustness.
  • Understanding this link can advance the study of epithelial morphogenesis.
  • This review highlights novel insights into the precision of biological development.