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Papillitis and uveitis complicating Bacillus Calmette-Guérin immunotherapy
Thomas P Toohey1, Sharon Wallace2, Michael G Toohey3
1Department of Ophthalmology, Prince of Wales Hospital and Community Health Services, Randwick, New South Wales, Australia tomtoohey93@gmail.com.
BMJ Case Reports
|May 23, 2022
Summary
This study reports a rare case of severe bilateral uveitis and papillitis following Bacillus Calmette-Guérin (BCG) treatment for bladder cancer. Prompt corticosteroid treatment led to vision recovery and symptom resolution.
Area of Science:
- Ophthalmology
- Oncology
- Immunology
Background:
- Intravesical Bacillus Calmette-Guérin (BCG) is a standard treatment for bladder carcinoma.
- Ocular side effects from BCG therapy are rare but can be severe.
- Hypersensitivity reactions to BCG are known, but specific ophthalmological manifestations vary.
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