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Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

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Published on: June 23, 2023

Binge drinking alongside alcoholic chronic abuse.

Jean-François Lesesve¹, Julien Perrin¹

¹Service d'hématologie biologique, centre hospitalier universitaire, Nancy, France.

Morphologie : Bulletin De L'Association Des Anatomistes

|May 23, 2022

Summary

This summary is machine-generated.

This case report details an adult with alcoholic cirrhosis and spur cell anemia, noting acute white blood cell vacuolation linked to recent binge alcohol consumption.

Keywords:

Acanthocyte Alcoholic liver disease Anemia Anémie Cirrhose hépatique Leucocytes vacuolés Spur cell Vacuolated leukocyte

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Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

Published on: January 7, 2019

Area of Science:

Internal Medicine
Hematology
Hepatology

Background:

Alcoholic cirrhosis is a severe liver condition often associated with hematological complications.
Spur cell anemia, characterized by acanthocytic red blood cells, can occur in end-stage liver disease.

Observation:

An adult patient presented with diagnosed ethylic cirrhosis.
The patient also exhibited symptoms of spur cell anemia.

Findings:

Acute vacuolation of leukocytes (white blood cells) was observed.
This leukocyte abnormality was directly correlated with recent episodes of binge drinking.

Implications:

Highlights a potential hematological marker (leukocyte vacuolation) associated with acute alcohol intake in cirrhotic patients.
Suggests further investigation into the mechanisms linking alcohol consumption, liver disease, and leukocyte morphology changes.