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Related Concept Videos

Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

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 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
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Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

42
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

41
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
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Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

29
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
29
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

40
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
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Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

1.3K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
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Related Experiment Video

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Diabetic Peripheral Neuropathy.

Johan Røikjer1,2,3, Niels Ejskjaer4,5,6

  • 1Steno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark.

Handbook of Experimental Pharmacology
|May 23, 2022
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Summary

Diabetic peripheral neuropathy, a common diabetes complication, lacks clear causes and effective treatments. This review updates knowledge on its background and treatment, outlining future research directions.

Keywords:
DiabetesNeuropathyPainfulPeripheralTreatment

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Area of Science:

  • Neurology
  • Endocrinology
  • Diabetology

Background:

  • Diabetic peripheral neuropathy is the most frequent complication of diabetes mellitus.
  • Its pathophysiology is not well understood, hindering effective clinical practice and research.
  • Current treatment options for diabetic neuropathy are limited.

Purpose of the Study:

  • To provide an update on the background of diabetic peripheral neuropathy.
  • To review current treatment strategies for diabetic neuropathy.
  • To outline future goals and perspectives for clinical and scientific approaches.

Main Methods:

  • Literature review and synthesis of existing research on diabetic neuropathy.
  • Analysis of current clinical and pharmacological trial data.
  • Discussion of future research needs and potential therapeutic targets.

Main Results:

  • The pathophysiology of diabetic neuropathy remains largely undescribed.
  • Robust clinical endpoints for trials are lacking.
  • Efficient and universally effective treatments are not available.

Conclusions:

  • Further research into the pathophysiology of diabetic neuropathy is crucial.
  • Development of standardized clinical endpoints is necessary for advancing treatment.
  • Novel therapeutic strategies are needed for early detection, prevention, and treatment of diabetic neuropathy.