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Updated: Sep 22, 2025

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth
Published on: May 17, 2024
The therapeutic effects of stem cells from human exfoliated deciduous teeth on clinical diseases: a narrative review
Fariba Naderi1, Mohsen Mehdiabadi1, Farideh Kamarehei2
1Pediatric Dentistry Department, Faculty of Dentistry, Hamadan University of Medical Sciences Hamadan, Iran.
Introduction:
Stem cells isolated from human dental pulp tissue are different from other sources of Mesenchymal stem cells because of their embryonic neural crest sources and neuro-trophic potential. These stem cells consist of dental pulp stem cells from human permanent teeth and stem cells from human exfoliated deciduous teeth.
Aim:
In this study, we survey the advantages and disadvantages of these stem cells with therapies attitude.
Main Text:
Stem cells from human exfoliated deciduous teeth with a high proliferation rate could distinguish into a wide types of cells. After stem cell banking appearance, stem cells from human exfoliated deciduous teeth can preserve and use for treatment, especially in regenerative medicine. But the crucial health hazards related to stem cell transplantation, such as immune rejection reactions and the interaction with other tissues, should not be neglected.
Conclusion:
Further experiments are required to approve the impact of these stem cells on different human disorders.
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14:52Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods
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