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Measurement of the Pressure-volume Curve in Mouse Lungs
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Physiologic-range flow and pressure sensor for respiratory systems.

Lui Holder-Pearson1, J Geoffrey Chase1

  • 1Centre for Bioengineering, University of Canterbury, New Zealand.

Hardwarex
|May 24, 2022
PubMed
Summary
This summary is machine-generated.

This study presents a low-cost Venturi tube and differential pressure sensor system for accurate medical flow and pressure measurement. The affordable system enhances development of medical equipment and respiratory function studies.

Keywords:
Customisable sensorMechanical ventilationRespiratory analysisReusable sensor

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Area of Science:

  • Biomedical Engineering
  • Medical Device Development
  • Respiratory Physiology

Background:

  • Accurate measurement of low-range pressures and flows is crucial for medical equipment and respiratory studies.
  • Existing sensors are often costly, hindering accessibility and development.
  • Development of low-cost, reliable sensors is an impediment.

Purpose of the Study:

  • To develop and validate a low-cost, reliable sensor system for measuring respiratory flow and pressure.
  • To assess the accuracy and performance of the proposed sensor configuration.
  • To provide an accessible solution for medical equipment development.

Main Methods:

  • Utilized a Venturi tube coupled with a differential pressure sensor (SDP816-125 Pa) for flow measurement.
  • Employed a MPVZ4006GW7U sensor for accurate pressure readings.
  • Configured sensors with a standard voltage supply for analog output, ensuring compatibility.

Main Results:

  • Achieved accurate flow measurement within a specified range (0-100 L/min) with high correlation coefficients (Pearson r > 0.99).
  • Demonstrated comparable accuracy for pressure measurements.
  • Developed a cost-effective system with populated PCBs at ~$50 USD and Venturi sensors at ~$1 USD.

Conclusions:

  • The developed low-cost Venturi tube and differential pressure sensor system offers reliable and accurate measurements for medical applications.
  • This system significantly reduces costs, facilitating advancements in medical equipment and respiratory function research.
  • The customizable configurations allow for adaptation to various flow rates and resolution requirements.