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Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
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Intraoperative hemostatic agents in orbital surgery.

Edward J Wladis1,2, George Stavropoulos1, Charlotte L Marous1

  • 1Ophthalmic Plastic Surgery, Department of Ophthalmology, Lions Eye Institute, Albany Medical College, Slingerlands, New York, USA.

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|May 24, 2022
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Summary

Intraoperative bleeding control in orbital surgery is crucial. New hemostatic technologies, including mechanical agents, flowable agents, and pro-thrombotic medications, offer improved surgical hemostasis.

Keywords:
Bleedinghemorrhagehemostasisorbital surgery

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Area of Science:

  • Ophthalmology
  • Surgical Innovation

Background:

  • Intraoperative bleeding management in orbital surgery is less understood than pre- and post-operative care.
  • Advances in other medical fields offer new opportunities for controlling bleeding during orbital procedures.

Purpose of the Study:

  • To review current and emerging technologies for managing intraoperative bleeding during orbital surgery.
  • To discuss the application of novel hemostatic modalities in the orbital context.

Main Methods:

  • A comprehensive literature search was conducted to identify relevant studies on intraoperative bleeding management.
  • Bibliographic analysis of identified manuscripts was performed to uncover additional references.
  • Data extraction from selected studies was systematically performed.

Main Results:

  • Several hemostatic agents are currently utilized in orbital surgery and related fields.
  • Effective hemostasis can be achieved through direct mechanical methods, flowable agents, and pro-thrombotic medications.

Conclusions:

  • Orbital surgeons have an expanding array of technologies to achieve intraoperative hemostasis.
  • Future research is expected to introduce more targeted medications and innovative delivery systems for enhanced intraoperative bleeding control.