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A Slice-Low-Rank Plus Sparse (slice-L + S) Reconstruction Method for k-t Undersampled Multiband First-Pass Myocardial
Changyu Sun1,2,3, Austin Robinson4, Yu Wang1
1Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia.
Magnetic Resonance in Medicine
|May 24, 2022
Summary
The new slice-L+S method improves multiband (MB) perfusion MRI by enhancing slice coverage and image quality. This technique outperforms previous methods, offering better results for accelerated MRI scans.
Area of Science:
- Magnetic Resonance Imaging (MRI)
- Medical Imaging Physics
Background:
- Multiband (MB) imaging combined with k-t undersampling can improve slice coverage and spatial resolution in first-pass perfusion MRI.
- The low-rank plus sparse (L+S) model is effective for accelerating single-band (SB) perfusion MRI.
Purpose of the Study:
- To develop and evaluate a novel data consistency method for MB perfusion MRI.
- To combine MB data consistency with temporal L+S constraints for improved reconstruction.
Main Methods:
- A MB data consistency method using ESPIRiT maps and through-plane coil information was developed.
- This method, termed slice-L+S, was integrated with temporal L+S constraints.
- Slice-L+S was compared against SB L+S and sequential split slice-GRAPPA with SB L+S (seq-SG-L+S) using synthetic and prospectively acquired MB data.
Main Results:
- Slice-L+S demonstrated superior performance over SB L+S and seq-SG-L+S in terms of normalized RMSE and structural similarity index on synthetic data (P<0.05).
- Reconstructions using slice-L+S showed better image quality compared to seq-SG-L+S for prospectively undersampled MB data, as assessed by blinded experts.
- Specific quantitative results showed slice-L+S achieving lower RMSE and higher structural similarity index values.
Conclusions:
- The developed slice-L+S method effectively reconstructs accelerated MB perfusion MRI data.
- Slice-L+S provides significant improvements in image quality and slice coverage for cardiac MRI.
- This method offers a promising approach for advanced perfusion imaging with high spatial resolution.

