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Related Concept Videos

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
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DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
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Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
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Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
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Related Experiment Video

Updated: Sep 22, 2025

3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans and Mouse
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Imaging perivascular space structure and function using brain MRI.

Giuseppe Barisano1, Kirsten M Lynch2, Francesca Sibilia2

  • 1Laboratory of Neuro Imaging, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, USA; Neuroscience Graduate Program, University of Southern California, Los Angeles, CA, USA.

Neuroimage
|May 24, 2022
PubMed
Summary
This summary is machine-generated.

This review covers advanced brain MRI techniques for studying perivascular spaces (PVS). These methods help understand PVS roles in fluid circulation, waste clearance, and neurological diseases.

Keywords:
Diffusion MRIPerivascular spacesStructural MRIUltra-high field MRI

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Area of Science:

  • Neuroimaging
  • Neuroscience
  • Radiology

Background:

  • Perivascular spaces (PVS) play a crucial role in cerebrospinal fluid circulation and the clearance of cerebral waste products.
  • Growing evidence links PVS dysfunction to various neurological diseases.
  • Accurate quantification and functional analysis of PVS are essential for understanding their role in health and disease.

Purpose of the Study:

  • To provide a comprehensive overview of current neuroimaging methods for studying human PVS using brain MRI.
  • To examine novel strategies and techniques for quantitative analysis of PVS structure and function.
  • To offer guidance on acquisition protocols and analysis techniques for in vivo PVS research.

Main Methods:

  • Review of advanced brain MRI techniques, including quantitative imaging and novel analysis strategies.
  • Description of methods for assessing PVS morphology and function in physiological and pathological conditions.
  • Guidance on optimal MRI acquisition protocols and data analysis for PVS studies.

Main Results:

  • Detailed examination of the applications, advantages, and limitations of various MRI methods for PVS quantification.
  • Overview of technological developments enhancing the study of PVS structure and function.
  • Synthesis of findings from human neuroimaging studies on PVS across the lifespan and in neurological disorders.

Conclusions:

  • Neuroimaging, particularly advanced MRI, offers powerful tools for studying PVS in vivo.
  • Improved methods enable better understanding of PVS involvement in neurological diseases.
  • This review provides a valuable resource for researchers investigating PVS across normative and pathological states.