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Cognitive Remediation and Social Recovery in Early Psychosis (CReSt-R): protocol for a pilot randomised controlled
E Frawley1, M Cowman1, M Cella2
1Centre for Neuroimaging, Cognition & Genomics (NICOG), School of Psychology, National University of Ireland, Galway, Ireland.
This study explores a new treatment combining cognitive remediation and cognitive behavioral therapy for early psychosis. The goal is to improve social recovery and cognitive function in young adults with psychosis.
Area of Science:
- Psychiatry
- Clinical Psychology
- Neuroscience
Background:
- Early psychosis significantly impacts young adults, causing more disability than paraplegia or blindness.
- Current treatments for psychosis primarily target positive symptoms, neglecting cognitive and social functional deficits.
Purpose of the Study:
- To evaluate the feasibility, acceptability, and effectiveness of a novel psychosocial intervention for early psychosis.
- To assess a combined cognitive remediation and cognitive behavioral therapy approach focused on social recovery.
Main Methods:
- A pilot randomized controlled trial (CReSt-R) involving participants aged 16-35 within 5 years of a psychotic disorder diagnosis.
- Recruitment from multiple clinical sites with intervention and assessment conducted by a central team.
- The intervention integrates cognitive remediation training and social recovery-focused cognitive behavioral therapy.
Main Results:
- The study aims to evaluate the feasibility and acceptability of the integrated intervention.
- It will explore the potential efficacy of the combined treatment approach.
Conclusions:
- Both cognitive remediation and cognitive behavioral therapy have shown individual effectiveness.
- This trial investigates the synergistic potential of combining these approaches into a multicomponent intervention for early psychosis.
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