Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anionic Chain-Growth Polymerization: Overview01:20

Anionic Chain-Growth Polymerization: Overview

2.2K
The polymerization process that involves carbanion as an intermediate is called anionic polymerization. It is also a type of addition or chain-growth polymerization. Anionic polymerization gets initiated by a strong nucleophile such as an organolithium or a Grignard reagent. The most commonly used initiator for anionic polymerization is butyl lithium. Monomers involved in anionic polymerization must possess a vinyl group bonded to one or two electron-withdrawing groups. For instance,...
2.2K
Step-Growth Polymerization: Overview01:03

Step-Growth Polymerization: Overview

3.7K
Step-growth or condensation polymerization is a stepwise reaction of bi or multifunctional monomers to form long-chain polymers. As all the monomers are reactive, most of the monomers are consumed at the early stages of the reaction to form small chains of reactive oligomers, which then combine to form long polymer chains in the late stages. Hence, the reaction has to proceed for a long time to achieve high molecular weight polymers.
Many natural and synthetic polymers are produced by...
3.7K
Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)00:53

Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)

2.0K
Acyclic diene metathesis polymerization or ADMET polymerization involves cross-metathesis of terminal dienes, such as 1,8-nonadiene, to give linear unsaturated polymer and ethylene. As ADMET is a reversible process, the formed ethylene gas must be removed from the reaction mixture to complete the polymerization process.
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...
2.0K
Free-Radical Chain Reaction and Polymerization of Alkenes02:35

Free-Radical Chain Reaction and Polymerization of Alkenes

8.2K
The conversion of alkenes to macromolecules called polymers is a reaction of high commercial importance. The structure of the polymer is defined by a repeating unit, while the terminal groups are considered insignificant. The average degree of polymerization represents the number of repeating units in the polymer molecule and is denoted by the subscript n.
8.2K
Polymer Classification: Architecture01:14

Polymer Classification: Architecture

3.1K
Polymers are classified as linear or branched on the basis of their chain architecture. The polymer chains in linear polymers have a long chain-like structure with minimal to no branching at all. Even if a polymer features large substituent groups on the monomer, which appear as branches to the skeleton, it is not considered a branched polymer. A branched polymer contains secondary polymer chains that arise from the main polymer chain. The branching occurs when the polymer growth shifts from...
3.1K
Olefin Metathesis Polymerization: Overview01:13

Olefin Metathesis Polymerization: Overview

2.3K
Recently, the development of olefin metathesis polymerization advanced the field of polymer synthesis. Simply put, the reorganization of substituents on their double bonds between two olefins in the presence of a catalyst is known as the olefin metathesis reaction. The use of metathesis reaction for polymer synthesis is called olefin metathesis polymerization.
Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists...
2.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anion exchange beads for PFAS capture using a polymerization-induced microphase separation approach.

RSC applied polymers·2026
Same author

Interfacial Dynamics Accelerate Aging Yet Sustain Toughness in Poly(l‑lactide) Block Polymer Plastics.

ACS central science·2026
Same author

Ionically Triggered Cleavage of Poly(ethylene glycol) End Capped with Calcium Alginate Oligomers.

Biomacromolecules·2026
Same author

Strategies toward Renewable and Compostable Intravenous Bag Materials.

ACS applied bio materials·2026
Same author

Permeability-Strength Trade-off in Nanoporous Polyethylene Membranes Derived from Etchable Triblock Polymer Precursors.

ACS applied materials & interfaces·2025
Same author

Spiers Memorial Lecture: Compostable plastics: promise and pitfalls.

Faraday discussions·2025
Same journal

Multitargeted Degradation of Cell Surface Receptors by Modular Glyco-Nanosheets.

ACS macro letters·2026
Same journal

Vinyl Ether Maleic Anhydride Copolymers: Efficient and Reusable Sorbents for Removing Heavy Metals from Water.

ACS macro letters·2026
Same journal

Topology-Preserving Elastic Deformation Augmentation Enables Robust Defect Detection in Data-Scarce Industrial Imagery.

ACS macro letters·2026
Same journal

Flexible Porous Organic Polymers with α,β-Enone-Linkage via AlCl<sub>3</sub>-Catalyzed Horner-Wadsworth-Emmons Polymerization for Pd Recovery.

ACS macro letters·2026
Same journal

Light-Controlled Topology Switching Enables Continuous Modulation of Thermally Induced Phase Behavior in Polymer Solutions.

ACS macro letters·2026
Same journal

Correction to "Light-Induced Transformation from Covalent to Supramolecular Polymer Networks".

ACS macro letters·2026
See all related articles

Related Experiment Video

Updated: Sep 22, 2025

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
15:33

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

29.2K

Activated Polyacrylamides as Versatile Substrates for Postpolymerization Modification.

Michael B Larsen1, Shannon E Herzog1, Helena C Quilter2

  • 1Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.

ACS Macro Letters
|May 25, 2022
PubMed
Summary
This summary is machine-generated.

This study introduces activated polyacrylamides via a novel postpolymerization modification. This method allows for versatile polymer synthesis, including copolymers for on-demand gelation and block polymers.

More Related Videos

Preparation of DNA-crosslinked Polyacrylamide Hydrogels
09:06

Preparation of DNA-crosslinked Polyacrylamide Hydrogels

Published on: August 27, 2014

14.8K
Preparation of Polypentafluorophenyl acrylate Functionalized SiO2 Beads for Protein Purification
08:51

Preparation of Polypentafluorophenyl acrylate Functionalized SiO2 Beads for Protein Purification

Published on: November 19, 2018

9.8K

Related Experiment Videos

Last Updated: Sep 22, 2025

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
15:33

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

29.2K
Preparation of DNA-crosslinked Polyacrylamide Hydrogels
09:06

Preparation of DNA-crosslinked Polyacrylamide Hydrogels

Published on: August 27, 2014

14.8K
Preparation of Polypentafluorophenyl acrylate Functionalized SiO2 Beads for Protein Purification
08:51

Preparation of Polypentafluorophenyl acrylate Functionalized SiO2 Beads for Protein Purification

Published on: November 19, 2018

9.8K

Area of Science:

  • Polymer Chemistry
  • Organic Synthesis
  • Materials Science

Background:

  • Postpolymerization modification is crucial for creating complex polymer architectures.
  • Activated polyacrylates are well-established, but analogous polyacrylamides are less explored.
  • Developing new activated polymer platforms is essential for advanced materials.

Purpose of the Study:

  • To synthesize a new class of activated polyacrylamides.
  • To investigate the transamidation of these polymers with various nucleophiles.
  • To demonstrate the utility of this method for creating functional polymers.

Main Methods:

  • Activation of acrylamide monomers with two tert-butyloxycarbamate (Boc) groups.
  • Radical polymerization of the activated monomers to form poly(di(Boc)-acrylamide).
  • Transamidation reactions with primary and secondary amines, and alcohols.

Main Results:

  • Successful synthesis of poly(di(Boc)-acrylamide) via radical polymerization.
  • High conversion achieved in transamidation with primary amines under mild conditions.
  • Demonstrated synthesis of copolymers for on-demand gel formation and block polymers.

Conclusions:

  • Activated polyacrylamides offer a versatile platform for polymer modification.
  • This method enables the synthesis of complex macromolecular structures.
  • The developed polymers show potential in applications like stimuli-responsive materials and advanced polymer architectures.