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Updated: Sep 22, 2025

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
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Amelotin Promotes Mineralization and Adhesion in Collagen-Based Systems

Yuichi Ikeda1,2, James Holcroft1, Eri Ikeda1,2,3

  • 1Faculty of Dentistry and Institute of Biomedical Engineering, University of Toronto, Toronto, Canada.

Cellular and Molecular Bioengineering
|May 25, 2022
PubMed
Summary

Recombinant human amelotin (rhAMTN) accelerates mineralization and enhances adhesion in collagen-based systems. This enamel matrix protein shows promise for developing improved barrier membranes for bone regeneration in periodontitis treatment.

Keywords:
BioengineeringDentinEnamel biomineralization/formationGuided tissue regenerationHydroxyapatite

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