Developing growth reference charts for the head circumference of Pakistani children aged 6 to 18 years

Muhammad Asif1, Muhammad Aslam2, Tariq Ismail3

  • 1Department of Statistics, Govt. Degree College, Qadir Pur Raan, Multan, Pakistan.

Insights

Pakistani children aged 6-18 have smaller head circumference (HC) percentiles compared to other countries. This study developed specific HC reference curves for Pakistani children, highlighting the need for country-specific growth charts.

Area of Science:

  • Pediatric anthropometry
  • Growth monitoring
  • Neurological development assessment

Background:

  • Head circumference (HC) is crucial for assessing brain volume and predicting developmental/neurological disorders in children.
  • Existing HC reference curves may not accurately represent diverse populations.
  • Establishing population-specific HC data is vital for accurate child health evaluations.

Purpose of the Study:

  • To develop smoothed reference curves for head circumference (HC) in Pakistani children aged 6 to 18 years.
  • To provide accurate anthropometric data for Pakistani pediatric populations.
  • To address the lack of localized HC growth charts.

Main Methods:

  • Utilized a cross-sectional dataset of 9,194 school-going children (ages 6-18).
  • Employed standard procedures for head circumference (HC) measurement in centimeters.
  • Applied the lambda-mu-sigma (LMS) statistical approach to generate smoothed centile curves for both sexes.
  • Compared Pakistani HC data with international references (US, Turkey).

Main Results:

  • HC increased with age in both boys and girls.
  • Boys exhibited larger HC percentiles than girls until age 10.
  • From age 11, girls showed higher upper percentiles (90th, 95th, 97th) than boys.
  • Pakistani children had smaller HC measurements across all ages compared to US and Turkish children.

Conclusions:

  • Significant disparities in HC percentiles exist between different countries.
  • International HC references (e.g., US CDC) are unsuitable for Pakistani children.
  • Developing country-specific HC reference curves is essential for accurate pediatric health assessment.
Abstract

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