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Updated: Sep 22, 2025
04:50
Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
Published on: May 16, 2025
354
Coral red beads and arthritis
Aparna Vyas1, Sreedhar Krishna1, Rajini Mahendran1
1Department of Dermatology, Croydon University Hospital, Croydon Health Services NHS Trust, London, UK.
Clinical and Experimental Dermatology
|May 25, 2022
Summary
This study details a patient with skin lesions and joint pain, diagnosed via histopathology. Findings revealed CD68 and CD45 positivity without cellular atypia, suggesting a specific inflammatory or immune response.
Area of Science:
- Dermatology
- Rheumatology
- Pathology
Background:
- Cutaneous papulonodular lesions and joint stiffness are complex symptoms requiring thorough investigation.
- Histopathological analysis is crucial for diagnosing various dermatological and rheumatological conditions.
Observation:
- A patient presented with distinct cutaneous papulonodular lesions.
- The patient also reported experiencing painful, stiff joints.
Findings:
- Histopathological examination of the lesions was performed.
- Immunohistochemistry revealed positivity for CD68 and CD45 markers.
- No evidence of cellular atypia was observed in the examined tissues.
Implications:
- The CD68 and CD45 positivity suggests an inflammatory or immune-mediated process involving macrophages and leukocytes.
- Absence of atypia indicates a non-neoplastic or non-malignant etiology.
- Further investigation may be warranted to determine the specific underlying condition causing these symptoms.
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