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Published on: May 4, 2020
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[Stress, asthenia and cognitive disorders].
E E Vasenina1, O A Gankina1, O S Levin1
1Russian Medical Academy of Continuous Professional Education, Moscow, Russia.
Summary
Asthenia, a sign of energy depletion, can become a disabling condition like chronic fatigue syndrome. It often co-occurs with cognitive and affective disorders, complicating diagnosis.
Area of Science:
- Neurology
- Immunology
- Psychiatry
Background:
- Asthenia, a common clinical syndrome, signals depleted energy resources and can stem from various somatic and neurological conditions.
- It can evolve into a severe, disabling pathological state, potentially becoming chronic fatigue syndrome, an immune-mediated disease.
- Asthenia frequently presents alongside affective and cognitive disorders, complicating accurate primary diagnosis.
Purpose of the Study:
- To investigate the complex interrelationships between asthenia, chronic fatigue syndrome, and associated cognitive and affective disorders.
- To elucidate the diagnostic challenges posed by the co-occurrence of these conditions.
Main Methods:
- Review of clinical manifestations and etiological factors of asthenia.
- Analysis of the progression from asthenia to chronic fatigue syndrome.
- Examination of the impact of concurrent cognitive and affective disorders on diagnosis.
Main Results:
- Asthenia's dual nature as a defense mechanism and a potential pathological entity is highlighted.
- The transformation of asthenia into chronic fatigue syndrome, an immune-mediated condition, is discussed.
- The significant diagnostic challenges arising from the frequent combination of asthenia with cognitive and affective symptoms are identified.
Conclusions:
- Understanding the intricate connections between asthenia, chronic fatigue syndrome, and mental health disorders is crucial for accurate diagnosis.
- Further research is needed to unravel the complex pathophysiology and improve diagnostic strategies for these overlapping conditions.
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