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Updated: Sep 22, 2025

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
A Clinical Decision Support System for Remote Monitoring of Cardiovascular Disease Patients: A Clinical Study
Filipa Ventura1, Pedro Sousa1,2, Maria Anjos Dixe2
1The Health Sciences Research Unit: Nursing (UICISA: E), Nursing School of Coimbra (ESEnfC), Coimbra, Portugal.
Insights
This study evaluates a Clinical Decision Support System (CDSS) to improve cardiac rehabilitation adherence for cardiovascular disease (CVD) patients using mobile health (mHealth) tools. The goal is to reduce recurrent cardiovascular events through personalized remote monitoring.
Area of Science:
- Cardiology
- Digital Health
- Health Services Research
Background:
- Cardiovascular diseases (CVD) are a leading global cause of death, with cardiac rehabilitation (CR) proven to reduce mortality and improve patient outcomes.
- Low adherence to traditional CR programs limits their effectiveness, highlighting the need for innovative, patient-centered approaches.
- Mobile health (mHealth) offers potential for personalized patient recommendations and remote monitoring in CR.
Purpose of the Study:
- To assess the effectiveness of a user-friendly Clinical Decision Support System (CDSS) for remote patient monitoring of CVD patients.
- To determine if the CDSS intervention can reduce recurrent cardiovascular events.
- To explore the integration of technological interfaces into CR programs.
Main Methods:
- A multicenter randomized controlled trial involving two cardiology units in Portugal.
- Prospective CVD patients will be screened for eligibility based on predefined criteria.
- The CDSS will generate personalized monitoring plans, recommend mHealth tools (apps, wearables), and collect patient data.
Main Results:
- This section is not yet available as the study started in January 2023 and findings will be published later.
Conclusions:
- The mHeart.4U intervention, utilizing a CDSS and mHealth, aims to enhance CR by providing personalized remote monitoring.
- Successful implementation could pave the way for integrating technological solutions into standard CR practices.
- The study is registered (NCT05196802) and ethical approval is pending, with findings to be disseminated in peer-reviewed journals.
Introduction:
Cardiovascular diseases (CVD) are the leading cause of death globally, taking an estimated 17. 9 million lives each year. Cardiac rehabilitation is shown to reduce mortality and hospital readmissions, while improving physical fitness and quality of life. Despite the recommendations and proven benefits, acceptance and adherence remain low. Mobile health (mHealth) solutions may contribute to more personalized and tailored patient recommendations according to their specific needs. This study protocol aims to assess the effectiveness of a user-friendly, comprehensive Clinical Decision Support System (CDSS) for remote patient monitoring of CVD patients, primarily on the reduction of recurrent cardiovascular events.
Methods And Analysis:
The study will follow a multicenter randomized controlled design involving two cardiology units in the Center Region of Portugal. Prospective CVD patients will be approached by the healthcare staff at each unit and checked for eligibility according to the predefined inclusion/exclusion criteria. The CDSS will suggest a monitoring plan for the patient, will advise the mHealth tools (apps and wearables) adapted to patient needs, and will collect data. The clinical study will start in January 2023.
Discussion:
The success of the mHeart.4U intervention will be a step toward the use of technological interfaces as an integrating part of CR programs.
Ethics And Dissemination:
The study will undergo ethical revision by the Ethics Board of the two hospital units where the study will unfold. The study was registered in ClinicalTrials.gov on 18th January 2022 with the number NCT05196802. The study findings will be published in international peer-reviewed scientific journals and encounters and in a user-friendly manner to the society.
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