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Related Concept Videos

Asepsis01:28

Asepsis

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The condition of being free from disease-causing living pathogens is asepsis. Aseptic techniques include a set of standard practices to achieve asepsis. An example is the regular environmental cleaning of all parts of the healthcare facility and hand hygiene at home before preparing or eating food. Medical and surgical asepsis in healthcare practice protects patients from harmful pathogens, minimizes the risk of contamination of susceptible sites, and reduces the risk of infection transmission.
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Urinary Tract Infection II: Pathophysiology01:25

Urinary Tract Infection II: Pathophysiology

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The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
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Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

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Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
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Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

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Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
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Pneumonia I: Introduction01:30

Pneumonia I: Introduction

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Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
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Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

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Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
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Related Experiment Video

Updated: Sep 22, 2025

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
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Sepsis in the Parturient.

Vanita Jain1, Aashima Arora1, Kajal Jain2

  • 1Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Indian Journal of Critical Care Medicine : Peer-Reviewed, Official Publication of Indian Society of Critical Care Medicine
|May 26, 2022
PubMed
Summary
This summary is machine-generated.

Sepsis in pregnant women is a major cause of illness and death, complicated by pregnancy-related physiological changes. Early diagnosis and tailored management are crucial for improving outcomes for both mother and baby.

Keywords:
PregnancyPregnancy complicationsSepsis

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A Controlled Mouse Model for Neonatal Polymicrobial Sepsis
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Area of Science:

  • Obstetrics and Gynecology
  • Critical Care Medicine
  • Infectious Diseases

Background:

  • Sepsis is a significant cause of maternal morbidity and mortality, with a high case fatality rate.
  • Pregnancy and puerperium present unique challenges for sepsis diagnosis due to physiological changes and overlapping symptoms.
  • Perinatal loss is a common consequence of sepsis in pregnant individuals.

Purpose of the Study:

  • To highlight the challenges in early sepsis identification in pregnant women.
  • To discuss the importance of timely management for maternal and perinatal outcomes.
  • To review current management strategies for sepsis in the parturient population.

Main Methods:

  • Review of existing literature and guidelines on sepsis management in pregnancy.
  • Extrapolation of Surviving Sepsis Campaign (SSC) guidelines with modifications for pregnant patients.
  • Consideration of physiological alterations during pregnancy and puerperium.

Main Results:

  • Pregnancy physiology increases susceptibility to sepsis and complicates diagnosis.
  • Polymicrobial infections are common in the puerperium, requiring broad-spectrum antibiotics.
  • Maternal resuscitation must prioritize fetal well-being and placental perfusion.
  • Delivery timing is guided by obstetric indications unless sepsis is intrauterine.

Conclusions:

  • Early identification and management are critical for improving maternal and perinatal outcomes in sepsis.
  • Sepsis management in pregnancy requires tailored approaches considering physiological changes.
  • Further research is needed to validate sepsis scoring systems in the parturient population.