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Liver Diseases in the Parturient.

Sridhar Sundaram1, Suprabhat Giri2

  • 1Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, Maharashtra, India.

Indian Journal of Critical Care Medicine : Peer-Reviewed, Official Publication of Indian Society of Critical Care Medicine
|May 26, 2022
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Summary

This study reviews liver diseases in pregnant women, emphasizing timely diagnosis and management for better maternal and fetal outcomes. Key considerations for managing these critical conditions during pregnancy are highlighted.

Keywords:
Acute fatty liver of pregnancyCholestasis of pregnancyHemolysis, elevated liver enzymes, and low platelets syndromePregnancy

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Area of Science:

  • Hepatology
  • Obstetrics
  • Critical Care Medicine

Background:

  • Liver diseases pose significant risks during pregnancy.
  • Parturients with liver conditions require specialized medical attention.
  • Understanding these diseases is crucial for effective management.

Purpose of the Study:

  • To provide a comprehensive overview of liver diseases in pregnant women.
  • To highlight diagnostic and management strategies.
  • To emphasize the importance of multidisciplinary care.

Main Methods:

  • Literature review of relevant studies on liver diseases in pregnancy.
  • Synthesis of current evidence on pathophysiology, diagnosis, and treatment.
  • Discussion of clinical implications and management guidelines.

Main Results:

  • Identified common liver diseases affecting pregnant individuals, including HELLP syndrome, acute fatty liver of pregnancy, and intrahepatic cholestasis of pregnancy.
  • Outlined key clinical features, diagnostic criteria, and laboratory findings for each condition.
  • Summarized evidence-based treatment and management approaches.

Conclusions:

  • Prompt diagnosis and appropriate management of liver diseases in parturients are essential for improving maternal and fetal outcomes.
  • A multidisciplinary approach involving obstetricians, hepatologists, and critical care physicians is recommended.
  • Further research is needed to optimize care for this patient population.