Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Aortic Regurgitation I: Introduction

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...

Mitral Stenosis I: Introduction

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...

Mitral Valve Prolapse I: Introduction

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...

Heart Valves

Heart Valves

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...

Aortic Regurgitation III: Medical Management

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Reevaluating Aortic Valve Neocuspidization in Children, Adolescents, and Young Adults: A Case Series Analysis.

World journal for pediatric & congenital heart surgery·2025

Same author

Long-term incidence of arrhythmias in extracardiac conduit Fontan and comparison between systemic left and right ventricle.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2024

Same author

Corrigendum: Case Report: Epstein-Barr virus and constrictive pericarditis-an unusual combination.

Frontiers in pediatrics·2024

Same author

Double-Outlet Left Ventricle: Case Series and Systematic Review of the Literature.

Diagnostics (Basel, Switzerland)·2023

Same author

Pediatric airway compression in aortic arch malformations: a multidisciplinary approach.

Frontiers in pediatrics·2023

Same author

Case report: Epstein-Barr virus and constrictive pericarditis-An unusual combination.

Frontiers in pediatrics·2023

Search research articles

Related Experiment Video

Updated: Sep 22, 2025

A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position

A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position

Published on: April 1, 2022

Pediatric aortic valve neocuspidization.

Adriano Carotti¹

¹Bambino Gesu' Children's Hospital Piazza S. Onofrio 4 Roma 00165 Italy.

Multimedia Manual of Cardiothoracic Surgery : MMCTS

|May 26, 2022

Summary

This summary is machine-generated.

Ozaki neocuspidization offers a promising surgical option for pediatric aortic valve disease. This technique reconstructs the aortic valve using autologous pericardium, addressing native valve incompetence in children.

Keywords:

AVNeo Aortic valve neocuspidization Aortic valve reconstruction Pediatric Ozaki operation

More Related Videos

Author Spotlight: Advancing Cardiac Procedure Testing Prior to Embarking on Large Animal Studies

Author Spotlight: Advancing Cardiac Procedure Testing Prior to Embarking on Large Animal Studies

Published on: August 25, 2023

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

Related Experiment Videos

Last Updated: Sep 22, 2025

A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position

A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position

Published on: April 1, 2022

Author Spotlight: Advancing Cardiac Procedure Testing Prior to Embarking on Large Animal Studies

Author Spotlight: Advancing Cardiac Procedure Testing Prior to Embarking on Large Animal Studies

Published on: August 25, 2023

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

Area of Science:

Cardiovascular Surgery
Pediatric Cardiology
Biomaterials in Medicine

Background:

Aortic valve disease in children presents complex treatment challenges.
The Ozaki neocuspidization technique is gaining attention for aortic valve reconstruction.
Autologous pericardium is utilized for neoaortic valve creation.

Observation:

This video tutorial details the Ozaki neocuspidization procedure.
The technique involves reconstructing a neoaortic valve using pretreated autologous pericardium.
A specific case of an incompetent native tricuspid aortic valve in a pediatric patient is presented.

Findings:

The Ozaki technique provides a method for aortic valve reconstruction in pediatric cases.
The use of autologous pericardium is demonstrated for neoaortic valve formation.
The tutorial illustrates the practical application of this surgical approach.

Implications:

This surgical approach may offer an alternative to traditional valve replacement in pediatric patients.
Further evaluation of neocuspidization outcomes in pediatric populations is warranted.
The technique holds potential for improving long-term valve function in young patients.