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[Allergies and dental pulp (author's transl)].

V W Adamkiewicz, D D Pekovic, C Mascrès

    Revue De Stomatologie Et De Chirurgie Maxillo-Faciale
    |January 1, 1978
    PubMed
    Summary

    Dental pulp allergy involves immune cells and molecules like histamine, but immediate allergic reactions are unproven. Cellular allergies, including graft rejection and contact hypersensitivity, along with autoimmunity, have been identified.

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    Area of Science:

    • Immunology
    • Oral Biology
    • Pathology

    Context:

    • The dental pulp, crucial for tooth vitality, can be affected by immune responses.
    • Inflammation in the dental pulp triggers the presence of various immune components.

    Purpose:

    • To review existing literature on allergic and immune-mediated conditions within the dental pulp.
    • To differentiate between immediate and delayed hypersensitivity reactions in pulpal tissue.

    Summary:

    • The inflamed dental pulp exhibits antigens, lymphocytes, plasma cells, immunoglobulins (IgG, IgA, IgE), mast cells, histamine, and complement (C3).
    • Immediate-type hypersensitivity mediated by circulating antibodies has not been demonstrated in the dental pulp.
    • Two forms of cellular allergy, graft rejection and contact hypersensitivity, have been described in the dental pulp.
    • Evidence for autoimmunity in the dental pulp has recently emerged.

    Impact:

    • Clarifies the immunological profile of the dental pulp in allergic and autoimmune contexts.
    • Highlights the absence of immediate hypersensitivity, directing focus towards cellular mechanisms.
    • Provides a foundation for understanding pulp pathology and developing targeted treatments for immune-related dental conditions.

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