Related Experiment Video
Updated: Sep 22, 2025

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
Evaluation of optimal Zernike radial degree for representing corneal surfaces
Pooria Omidi1, Alan Cayless2, Achim Langenbucher1
1Department of Experimental Ophthalmology, Saarland University, Homburg/Saar, Germany.
Abstract:
Tomography data of the cornea usually contain useful information for ophthalmologists. Zernike polynomials are often used to characterize and interpret these data. One of the major challenges facing researchers is finding the appropriate number of Zernike polynomials to model measured data from corneas. It is undeniable that a higher number of coefficients reduces the fit error. However, utilizing too many coefficients consumes computational power and time and bears the risk of overfitting as a result of including unnecessary components. The main objective of the current study is to analyse the accuracy of corneal surface data modelled with Zernike polynomials of various degrees in order to estimate a reasonable number of coefficients. The process of fitting the Zernike polynomials to height data for corneal anterior and posterior surfaces is presented and results are shown for normal and pathological corneas. These results indicate that polynomials of a higher degree are required for fitting corneas of patients with corneal ectasia than for normal corneas.
Related Concept Videos
Degree of Curvature and Radius of Curvature
Radius of Gyration of an Area
Region of Convergence
Spherical Coordinates
Focusing of Light in the Eye
Inverse z-Transform by Partial Fraction Expansion
To begin the process, the poles of the function are identified and the function is...

