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Radiologic Evaluation Criteria for Chronic Subdural Hematomas: Recommendations for Clinical Trials.

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Middle meningeal artery embolization shows promise for chronic subdural hematomas. Standardizing outcome measures in trials is crucial for accurate results and informing clinical practice.

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Area of Science:

  • Neurology
  • Interventional Radiology

Background:

  • Middle meningeal artery embolization is an emerging treatment for chronic subdural hematomas.
  • Current chronic subdural hematoma trials require standardized definitions and accurate evaluations to inform clinical practice.

Purpose of the Study:

  • To summarize current practices in chronic subdural hematoma evaluation.
  • To propose standardized, image-based outcome measures for future chronic subdural hematoma trials.

Main Methods:

  • A living review was conducted using the {Nested} Knowledge AutoLit platform.
  • Commonly reported data elements were identified to derive suggestions for reporting standards.

Main Results:

  • A set of standardized image-based study endpoints for chronic subdural hematoma evaluation was proposed.
  • Proposed measurement methods and reporting standards are based on published best practices.

Conclusions:

  • Standardizing radiologic outcome measures and techniques in embolization trials will enhance trial impact and data pooling.
  • Standardization facilitates increased statistical power and translation of trial results to clinical practice.