Hyperthyroidism and the Risk of Cardiac Arrhythmias: A Narrative Review

Mahlika Ahmad1, Sanjana Reddy2, Zineb Barkhane3

  • 1Internal Medicine, Ziauddin University, Karachi, PAK.

Cureus
|May 27, 2022
PubMed

Insights

Hyperthyroidism significantly increases the risk of heart rhythm problems like atrial fibrillation (AF). Managing thyroid hormones and arrhythmias is crucial for cardiovascular health.

Area of Science:

  • Cardiology
  • Endocrinology
  • Internal Medicine

Background:

  • Hyperthyroidism adversely impacts cardiovascular function.
  • Thyroid hormone excess elevates the risk of cardiac arrhythmias, especially atrial fibrillation (AF).

Purpose of the Study:

  • To review hemodynamic changes and arrhythmia risks in hyperthyroidism.
  • To explore the pathophysiology and treatment of thyrotoxic AF and sinus tachycardia.

Main Methods:

  • Literature review of hemodynamic alterations.
  • Analysis of studies on cardiac arrhythmias in hyperthyroidism.
  • Discussion of treatment modalities for thyrotoxicosis-induced arrhythmias.

Main Results:

  • Hyperthyroidism is linked to increased prevalence and risk of cardiac arrhythmias.
  • Atrial fibrillation and sinus tachycardia are the most common arrhythmias in thyrotoxicosis.
  • Various treatments, including anti-thyroid drugs, beta-blockers, cardioversion, and ablation, are discussed.

Conclusions:

  • Hyperthyroidism poses a significant threat to cardiovascular health, primarily through arrhythmias.
  • Effective management of thyroid hormone levels and arrhythmias is essential.
  • Further research into the multi-level pathophysiology of thyrotoxic AF is warranted.

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