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The Value of Four Anthropometric Indicators for Identifying Left Ventricular Hypertrophy in Chinese Hypertensive
Bokai Cheng1,2, Nan Lu1,3, Ge Song2
1Medical School of Chinese PLA, Chinese PLA General Hospital, Beijing, China.
Insights
Obesity indices like BMI and waist circumference are linked to left ventricular hypertrophy (LVH) in hypertensive patients. Managing weight may help lower the risk of developing LVH.
Area of Science:
- Cardiology
- Public Health
- Anthropometry
Background:
- Left ventricular hypertrophy (LVH) is an independent risk factor for hypertension.
- Previous studies have not compared various body size indices with LVH in hypertensive populations.
Purpose of the Study:
- To investigate the association between different anthropometric indices and LVH in a hypertensive population in rural China.
- To identify obesity indicators as risk factors for LVH.
Main Methods:
- Analysis of anthropometric indices and cardiovascular disease risk factors in 4,639 hypertensive patients.
- Utilized Spearman's correlation, logistic regression, and ROC curve analyses.
- Compared patients in the highest quartile of body size indices to the lowest.
Main Results:
- Higher quartiles of BMI, WC, WHR, and WHtR were associated with increased likelihood of LVH.
- Adjusted odds ratios for LVH were significant for BMI (3.55), WC (2.23), WHR (1.44), and WHtR (3.23).
- ROC curve analysis indicated that BMI, WHtR, WHR, and WC are potential indicators associated with LVH.
Conclusions:
- Four anthropometric indicators of obesity (BMI, WC, WHR, WHtR) are identified as risk factors for LVH in hypertensive individuals.
- Weight control strategies may be beneficial in reducing the risk of developing left ventricular hypertrophy.
Abstract:
Left ventricular hypertrophy (LVH) has been classified separately as an independent risk factor for hypertension. However, comparisons between different body size indices and left ventricular hypertrophy (LVH) in hypertensive populations have not been reported yet. In this study, we enrolled 4,639 hypertensive patients from rural China. Anthropometric indices and cardiovascular disease risk factor variables were measured and analyzed using Spearman's correlation, logistic regression, and receiver operating characteristic (ROC) curve analyses. Patients in the highest quartile of body size indices were more likely to have left ventricular hypertrophy than those in the lowest quartile; these indices were BMI (adjusted OR: 3.55, 95% CI: 2.90; 4.35), WC (adjusted OR: 2.23, 95% CI: 1.84; 2.70), WHR (adjusted OR: 1.44, 95% CI: 1.18; 1.75), and WHtR (adjusted OR: 3.23, 95% CI: 2.62; 3.99). The areas under the ROC curves of BMI (AUC: 0.628, 95% CI: 0.612; 0.644), WHtR (AUC: 0.628, 95% CI: 0.560; 0.593), WHR (AUC: 0.530, 95% CI: 0.513; 0.547), and WC (AUC: 0.576, 95% CI: 0.513; 0.547) were all above 0.5, which indicated that the four anthropometric indicators may be associated with LVH. The four anthropometric indicators of obesity were identified as risk factors for LVH. Weight control might help reduce the risk of left ventricular hypertrophy.
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