The Value of Four Anthropometric Indicators for Identifying Left Ventricular Hypertrophy in Chinese Hypertensive

Bokai Cheng1,2, Nan Lu1,3, Ge Song2

  • 1Medical School of Chinese PLA, Chinese PLA General Hospital, Beijing, China.

Insights

Obesity indices like BMI and waist circumference are linked to left ventricular hypertrophy (LVH) in hypertensive patients. Managing weight may help lower the risk of developing LVH.

Area of Science:

  • Cardiology
  • Public Health
  • Anthropometry

Background:

  • Left ventricular hypertrophy (LVH) is an independent risk factor for hypertension.
  • Previous studies have not compared various body size indices with LVH in hypertensive populations.

Purpose of the Study:

  • To investigate the association between different anthropometric indices and LVH in a hypertensive population in rural China.
  • To identify obesity indicators as risk factors for LVH.

Main Methods:

  • Analysis of anthropometric indices and cardiovascular disease risk factors in 4,639 hypertensive patients.
  • Utilized Spearman's correlation, logistic regression, and ROC curve analyses.
  • Compared patients in the highest quartile of body size indices to the lowest.

Main Results:

  • Higher quartiles of BMI, WC, WHR, and WHtR were associated with increased likelihood of LVH.
  • Adjusted odds ratios for LVH were significant for BMI (3.55), WC (2.23), WHR (1.44), and WHtR (3.23).
  • ROC curve analysis indicated that BMI, WHtR, WHR, and WC are potential indicators associated with LVH.

Conclusions:

  • Four anthropometric indicators of obesity (BMI, WC, WHR, WHtR) are identified as risk factors for LVH in hypertensive individuals.
  • Weight control strategies may be beneficial in reducing the risk of developing left ventricular hypertrophy.

Related Concept Videos

Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
71
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
64
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
62