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Effect of hyperglycemia treatment on complications rate after pediatric cardiac surgery

Bahman Naghipour1, Mahdieh Bagerpour2, Kamran Shadvar1

  • 1Department of Anesthesiology and Intensive Care, Medical Faculty, Tabriz University of Medical Sciences, Tabriz, Iran.

Journal of Cardiovascular and Thoracic Research
|May 27, 2022
PubMed

Insights

Controlling blood sugar during pediatric cardiac surgery reduces complications. Accurate glucose management with insulin infusion shortened hospitalization and extubation times in children undergoing cardiopulmonary bypass.

Area of Science:

  • Pediatric Cardiac Surgery
  • Anesthesiology
  • Endocrinology

Background:

  • Intraoperative hyperglycemia is a concern in pediatric cardiac surgery.
  • Elevated blood glucose levels can lead to adverse outcomes.
  • Effective blood sugar control strategies are needed.

Purpose of the Study:

  • To investigate the complications of intraoperative hyperglycemia in children undergoing cardiac surgery.
  • To evaluate the benefits of insulin administration for precise blood glucose management.

Main Methods:

  • Randomized clinical trial involving 50 children under 12 undergoing cardiac surgery with cardiopulmonary bypass.
  • Intraoperative intravenous insulin infusion targeting blood glucose of 110-140 mg/dL.
  • Regular monitoring of blood glucose and arterial blood gas (ABG) every 30 minutes.

Main Results:

  • The insulin group required less inotrope use compared to the placebo group.
  • Hospitalization and extubation times were significantly shorter in the insulin group (P=0.03 and P=0.005, respectively).
  • No significant difference in ICU hospitalization duration between groups.

Conclusions:

  • Intraoperative hyperglycemia is linked to prolonged intubation and hospitalization.
  • Accurate blood glucose control using insulin infusion positively impacts outcomes.
  • This strategy helps reduce complications and shorten hospital stays in pediatric cardiac surgery patients.

Keywords:
Cardiac Surgical ProceduresHeartHyperglycemiaPediatricsThoracic SurgeryTreatment and Complications

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