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Published on: December 11, 2017
Aortic arch repair: lessons learned over three decades at Baylor College of Medicine
Arsalan Amin1, Ginger M Etheridge1, Hiruni S Amarasekara1
1Baylor College of Medicine, Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Houston, TX, USA.
Insights
This study details advancements in open aortic arch repair techniques over three decades, improving patient outcomes. Key changes include shifting cannulation sites and evolving brain protection strategies for complex aortic arch disease.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Vascular Surgery
Background:
- Complex aortic arch disease presents significant surgical challenges, carrying high risks of mortality and stroke.
- Over 3000 aortic arch repairs have been performed by the single-practice service since 1990.
- Surgical techniques for open aortic arch repair have undergone substantial evolution over the past thirty years.
Purpose of the Study:
- To describe the progression of technical approaches in open aortic arch repair.
- To highlight advancements in surgical strategies and brain protection during these demanding procedures.
Main Methods:
- Shift from femoral artery cannulation to innominate and axillary artery cannulation.
- Transition from retrograde cerebral perfusion to antegrade cerebral perfusion for enhanced brain protection.
- Evolution of brain protection from profound hypothermia (≤14 °C) to moderate hypothermia (22-24 °C) during circulatory arrest.
Main Results:
- The evolution in cannulation and perfusion strategies facilitates management of complex arch repairs.
- Modified hypothermia protocols represent a significant advancement in brain protection during aortic arch surgery.
- Surgical approaches encompass a range of aortic pathologies including dissections and aneurysms, often involving reoperative sternotomy.
Conclusions:
- Continuous refinement of surgical techniques, including cannulation and cerebral protection, has improved open aortic arch repair.
- Modern approaches allow for more effective treatment of complex aortic arch disease, potentially reducing associated risks.
- The described evolution reflects a commitment to advancing the standard of care for aortic arch pathologies.
Abstract:
The treatment of complex aortic arch disease continues to be among the most demanding cardiovascular operations, with a considerable risk of death and stroke. Since January 1990, our single-practice service has performed over 3000 repairs of the aortic arch. Our aim was to describe the progression of our technical approach to open aortic arch repair. Our center's surgical technique has evolved considerably over the last three decades. When it comes to initial arterial cannulation, we have shifted away from femoral artery cannulation to innominate and axillary artery cannulation. During difficult repairs, this transition has made it easier to use antegrade cerebral perfusion rather than retrograde cerebral perfusion, which was commonly used in the early days. Brain protection tactics during open aortic arch procedures have evolved from profound (≤14 °C) hypothermia during circulatory arrest to moderate (22-24 °C) hypothermia. Aortic arch repair is performed through a median sternotomy and may treat acute aortic dissection, chronic aortic dissection, or degenerative aneurysm. Reoperative repair - that necessitating redo sternotomy - is common in patients undergoing aortic arch repair. The majority of repairs will include varying portions of the ascending aorta and may involve the aortic valve or the aortic root. In some patients, repair may extend into the proximal descending thoracic aorta; this includes elephant trunk, frozen elephant trunk, and antegrade hybrid approaches.
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