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Updated: Sep 21, 2025

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Published on: May 23, 2025
Ultrasound-based navigation for open liver surgery using active liver tracking.
Jasper N Smit1, Koert F D Kuhlmann2, Oleksandra V Ivashchenko2,3
1Department of Surgical Oncology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands. j.smit@nki.nl.
This study introduces an image-guided navigation system for liver surgery, improving lesion localization by overlaying preoperative scans onto intraoperative ultrasound. The system achieved accuracy below 10 mm, enhancing surgical reliability.
Area of Science:
- Surgical Navigation
- Medical Imaging
- Hepatobiliary Surgery
Background:
- Intraoperative localization of liver lesions after systemic treatment remains challenging despite preoperative imaging.
- An image-guided navigation system was developed to integrate preoperative data with intraoperative ultrasound (US).
Purpose of the Study:
- To assess the workflow and accuracy of a novel navigation system that compensates for liver motion.
- To enable overlay of detailed preoperative diagnostic images onto intraoperative US for enhanced visualization.
Main Methods:
- Electromagnetic (EM) tracking for organ and transducer motion compensation.
- Landmark-based registration using preoperative 3D models and intraoperative ultrasound.
- Fixation of a liver sensor near the target lesion to account for local movement.
Main Results:
- 22 navigated procedures were successfully performed.
- Mean fiducial registration error was 10.3 ± 4.3 mm; mean target registration error was 8.5 ± 4.2 mm.
- Navigation system was available after an average of 12.7 minutes.
Conclusions:
- A novel navigation method combining ultrasound and active liver tracking was developed, achieving accuracy below 10 mm.
- The system effectively compensates for liver motion, improving surgical navigation reliability.
- This advancement offers significant potential for enhanced intraoperative guidance in liver procedures.
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