Related Experiment Video
Updated: Sep 21, 2025
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Association between serum 25-hydroxy vitamin D levels and severity of asthma
Samrad Mehrabi1, Elham Toghraee2
1Division of Pulmonology, Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Background & Aims:
Asthma prevalence has increased significantly since the 1960s. Increased airway hyperresponsiveness, decreased pulmonary function, poor asthma management, and steroid resistance have all been linked to vitamin D insufficiency. In addition, treatment with oral corticosteroids increases the risk of vitamin D deficiency. We studied patients with asthma regarding their vitamin D status and its association with disease severity.
Methods:
Patients with asthma were included in the study. Spirometry results and serum levels of 25-hydroxyvitamin D, calcium, and phosphorus were measured.
Results:
Of the 54 subjects, the majority (77.8%) were women, and the mean age was 49.71 ± 12.16 years. Among the patients, 19 (35.2%) had sufficient vitamin D levels, 18 (33.3%) had insufficient vitamin D, and 17 (31.5%) had vitamin D deficiency. The mean FEV/FVC in the group with vitamin D deficiency is significantly lower than those with insufficient vitamin D levels (P = 0.018). The mean calcium and phosphorus levels between the three groups were not different.
Conclusion:
Vitamin D deficiency is common in patients with asthma but is not associated with lung function test results.
More Related Videos
05:31Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
06:34A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
Related Concept Videos
01:24Asthma-III: Symptoms and Complications
Classification of Asthma
01:30Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
01:26Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
01:29Asthma-I: Introduction
01:20Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
01:23Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...