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Published on: May 11, 2018
Global best practices consensus: Long-term management of patients with hybrid centrifugal flow left ventricular
Christopher Hayward1, Iki Adachi2, Sylvie Baudart3
1Heart Failure and Transplant Unit, St Vincent's Hospital, Sydney, Australia.
Insights
This guideline offers best practices for managing patients with the HeartWare HVAD System, addressing the declining global expertise. It highlights key differences compared to the HeartMate 3 ventricular assist device.
Area of Science:
- Cardiology
- Medical Devices
- Mechanical Circulatory Support
Background:
- The HeartWare HVAD System (HVAD) remains implanted in approximately 4000 patients post-withdrawal from sale.
- Diminishing global experience necessitates updated management strategies for ongoing HVAD support.
Purpose of the Study:
- To provide a global consensus document summarizing key management recommendations for patients with ongoing HVAD support.
- To highlight differences in management compared to the HeartMate 3 ventricular assist device.
Main Methods:
- International experts in HVAD management convened to summarize patient and pump management.
- Clinicians from high-implant HVAD centers reviewed literature and shared experiences to form a consensus.
- Key differences in managing patients with the HeartMate 3 were identified.
Main Results:
- A guideline document with specific protocols and techniques for ongoing HVAD patient management was developed.
- Best practice techniques from international centers are summarized.
- Differences in approach to HeartMate 3 management are highlighted.
Conclusions:
- This consensus guideline addresses the decreasing worldwide experience in HVAD patient management.
- It offers a summary of best practices from international centers for ongoing HVAD support.
- Key differences in HeartMate 3 management are emphasized.
Objectives:
Six months after withdrawal of the HeartWare HVAD System (HVAD; Medtronic) from sale, approximately 4000 patients continue ongoing support with this device. In light of the diminishing experience, this global consensus document summarizes key management recommendations.
Methods:
International experts with experience in the management of patients with ongoing HVAD support were invited to summarize key aspects of patient and pump management and highlight differences in the current HeartMate 3 (Abbott Laboratories) ventricular assist device. Clinicians from high-implanting HVAD sites reviewed current literature and reported experience to generate a consensus statement.
Results:
Specific guidelines to assist in the management of ongoing HVAD patients are developed. Key management protocols and helpful techniques developed from experienced clinicians are combined into a short guideline document. As experience with HeartMate 3 increases, key differences in approach to management are highlighted, where appropriate.
Conclusions:
With decreasing worldwide experience in the ongoing management of HVAD-supported patients, this consensus guideline provides a summary of best practice techniques from international centers. Differences in HeartMate 3 management are highlighted.
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