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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Obesogens in Foods.

Iva Kladnicka1,2, Monika Bludovska1,3, Iveta Plavinova1

  • 1Department of Public Health and Preventive Medicine, Faculty of Medicine in Pilsen, Charles University, 301 00 Pilsen, Czech Republic.

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Environmental obesogens (endocrine-disrupting chemicals) contribute to rising global obesity by impacting metabolic pathways and potentially causing epigenetic changes. Foods, especially processed ones, are a primary source of these chemicals.

Keywords:
adipose tissuefoodmetabolic disruptorsmetabolic syndromeobesityobesogenssystematic low-grade inflammation

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Area of Science:

  • Environmental health
  • Endocrinology
  • Toxicology

Background:

  • Rising global obesity rates over the past forty years correlate with increased exposure to environmental endocrine-disrupting chemicals known as obesogens.
  • Obesogens may impact individuals and their progeny by epigenetically altering developmental set-points for body weight and composition.
  • These chemicals interfere with numerous neuro-endocrine-immune metabolic regulatory pathways, affecting processes like adipogenesis, lipogenesis, lipolysis, immunity, appetite, and gut microbiota.

Purpose of the Study:

  • To provide a comprehensive overview of obesogens.
  • To detail the occurrence of obesogens in food.
  • To elucidate the impact of obesogens on the human organism.

Main Methods:

  • Literature review of evidence-based medical data.
  • Analysis of scientific studies on obesogen exposure and health outcomes.
  • Examination of food sources and chemical contaminants/additives.

Main Results:

  • Growing evidence links specific obesogens to an increased risk of obesity.
  • Foods are identified as the primary route of human exposure to obesogens.
  • Obesogens are present in food naturally, as contaminants, or as additives, particularly in highly processed foods.

Conclusions:

  • Obesogens are significant environmental factors contributing to the obesity epidemic.
  • Understanding obesogen sources in food is crucial for public health interventions.
  • Further research is needed to fully comprehend the long-term health consequences of obesogen exposure.