Related Experiment Video
Updated: Sep 21, 2025
07:22
Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
8.5K
Hypersensitivity Reactions to Iodinated Contrast Media
Tsu-Man Chiu1,2, Sung-Yu Chu3
1Department of Dermatology, Changhua Christian Hospital, Changhua City 50073, Taiwan.
Biomedicines
|May 28, 2022
Summary
Iodinated contrast media (ICM) hypersensitivity, though rare, can be severe. A history of hypersensitivity is the main risk factor, necessitating careful management and documentation for patient safety.
Area of Science:
- Radiology
- Pharmacology
- Allergy and Immunology
Background:
- Iodinated contrast media (ICM) are widely used in medical imaging.
- While generally safe, ICM can cause adverse drug reactions (ADRs), ranging from mild to life-threatening hypersensitivity.
- Understanding and managing ICM hypersensitivity is crucial for patient care.
Purpose of the Study:
- To review essential knowledge regarding iodinated contrast media hypersensitivity for healthcare professionals.
- To outline strategies for managing patients at risk of ICM hypersensitivity.
- To emphasize the importance of accurate diagnosis and prevention.
Main Methods:
- Literature review on iodinated contrast media hypersensitivity.
- Analysis of risk factors, diagnostic methods, and management strategies.
- Synthesis of current recommendations for clinical practice.
Main Results:
- A history of ICM hypersensitivity is the primary risk factor.
- Premedication requires careful consideration in high-risk populations due to potential breakthrough reactions.
- Diagnostic tests (skin, in vitro, provocation) can aid in identifying safer alternatives for patients with severe reactions.
- Excipients within ICM can also trigger hypersensitivity.
- Standardized documentation is vital for diagnosis and prevention.
Conclusions:
- Effective management of ICM hypersensitivity relies on recognizing risk factors and employing appropriate diagnostic and preventive measures.
- Careful patient selection, risk assessment, and documentation are key to minimizing adverse events.
- Further research may be needed to refine diagnostic and management protocols for rare hypersensitivity reactions.
Related Concept Videos
01:30Radiological Investigation I: X-ray and CT
435
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
435
01:30Hypersensitivities
1.1K
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
1.1K
01:27Allergic Drug Reactions
1.0K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.0K
01:27Imaging Studies III: Computed Tomography
60
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
60
01:28Imaging Studies for Cardiovascular System V: CT
75
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
75
01:14Imaging Studies I: CT and MRI
471
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
471