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Updated: Sep 21, 2025

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K-8 Classroom Self-Collection Using XpressCollect Nasal Swab: A Usability and Efficacy Study.

Kate Cox1, Laura Haggerty1, Kate Abeln1

  • 1HS Design, Morristown, NJ 07960, USA.

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|May 28, 2022
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Summary
This summary is machine-generated.

Kindergarten through eighth-grade students can effectively self-collect nasal specimens using the XpressCollect swab with teacher guidance. Laboratory analysis confirmed adequate sample collection for disease determination in a classroom setting.

Keywords:
COVID-19SARS-CoV-2 testingnasal swabschool testingself-collection

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Area of Science:

  • Pediatric Health
  • Clinical Diagnostics
  • Public Health Surveillance

Background:

  • Effective specimen collection is crucial for accurate disease diagnosis and surveillance.
  • Previous methods may pose challenges for self-collection in younger populations.
  • Optimizing sample collection methods can improve accessibility and participation in health studies.

Purpose of the Study:

  • To evaluate the feasibility and effectiveness of the XpressCollect nasal swab for self-collection by students in kindergarten through eighth grade.
  • To assess the quality of self-collected specimens using ribonuclease P (RNase P) as an indicator of adequate sampling.
  • To optimize instructional materials for student-led nasal specimen collection.

Main Methods:

  • A phased study involving interviews with parents and teachers to refine the XpressCollect usability and instructional materials.
  • Classroom-based trials where teachers guided students (K-8) in self-collecting anterior nares specimens using XpressCollect.
  • Laboratory analysis of collected specimens for the presence of ribonuclease P (RNase P) to determine sample adequacy.

Main Results:

  • Teacher and parent feedback informed the development and optimization of user-friendly instructional materials.
  • Students across all tested grades (K-8) successfully self-collected nasal specimens with XpressCollect under teacher supervision.
  • Laboratory results indicated acceptable ribonuclease P Ct values, confirming adequate sample adequacy for all student-collected specimens.

Conclusions:

  • The XpressCollect nasal swab is a viable tool for self-collection of anterior nares specimens by students in kindergarten through eighth grade.
  • Teacher-guided, classroom-based self-collection using XpressCollect yields adequate specimens for diagnostic testing.
  • This method enhances the potential for large-scale, school-based health surveillance and testing initiatives.