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Evaluating Providers' Prescription Opioid Instructions to Pediatric Patients
Denise D Tran1, Patrick C M Brown2, Corrin Murphy2
1Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Insights
Pediatric opioid prescriptions lack crucial safety information. Many labels omit reasons for use, weaning instructions, and disposal guidance, increasing risks for young adults.
Area of Science:
- Pediatric pharmacology
- Public health
- Medication safety
Background:
- Childhood opioid prescriptions elevate hazardous use risk in emerging adulthood.
- Clear instructions are vital for safe pediatric opioid use and discontinuation.
Purpose of the Study:
- To evaluate the completeness of prescription opioid (PO) label instructions for pediatric outpatients.
- To identify deficiencies in PO instructions to improve patient safety and comprehension.
Main Methods:
- Retrospective analysis of electronic health records for 12,613 pediatric patients (0-17 years) receiving POs (2016-2019).
- Automated text classification used to examine medication instructions, diagnoses, and prescription details.
- Exclusion of patients with chronic conditions or inpatient PO use.
Main Results:
- 20.8% of PO labels lacked indication/reason for use.
- Over 99% of labels omitted instructions for weaning, disposal, or contact information for questions.
- Significant gaps exist in essential PO guidance for pediatric patients.
Conclusions:
- Pediatric PO label instructions are critically incomplete, lacking vital safety information.
- Improvements are urgently needed to ensure comprehensive instructions for safe PO use and management in children.
- Addressing these gaps can mitigate risks associated with pediatric prescription opioid use.
Abstract:
Receiving an opioid prescription during childhood increases the risk of hazardous prescription opioid (PO) use during emerging adulthood. Instruction on how to safely use POs plays an essential role in pediatric patients’ capacity to utilize as well as to discontinue POs appropriately. This study aimed to evaluate pediatric PO label instructions provided to a large sample of pediatric outpatients. Data were extracted from the electronic healthcare records system identifying pediatric patients who received a PO between 2016 and 2019 from pediatric outpatient medical clinics were affiliated with a northwestern United States medical center and children’s hospital. Pediatric patients (n = 12,613) between 0−17 years old who received a PO during outpatient care were included. Patients with chronic health conditions (e.g., cancer) or who received their PO from an inpatient medical setting were excluded. Patient demographics, medication instructions, associated diagnoses, and other prescription information (e.g., name of medication, dose, and quantity dispensed) were examined using automated text classification. Many label instructions did not include any indication/reason for use (20.8%). Virtually none of the POs (>99%) included instructions for how to reduce/wean off POs, contact information for questions about the POs, and/or instructions around how to dispose of the POs. Efforts are needed to ensure that pediatric PO instructions contain essential elements to improve comprehension of when and how to use POs for pediatric patients.
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