Related Experiment Video
Updated: Sep 21, 2025

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Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
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Socioeconomic Status and Interest in Genetic Testing in a US-Based Sample
E J Dusic1, Deborah J Bowen2, Robin Bennett3
1Institute of Public Health Genetics, University of Washington, Seattle, WA 98105, USA.
Healthcare (Basel, Switzerland)
|May 28, 2022
Summary
Socioeconomic status impacts interest in hereditary cancer genetic testing. Higher education and income increase general interest, while lower subjective social status boosts interest in free or low-cost testing.
Area of Science:
- Medical Genetics
- Public Health
- Cancer Prevention
Background:
- Cancer disproportionately affects individuals of lower socioeconomic status (SES).
- Hereditary cancer genetic testing offers personalized risk assessment and preventative strategies.
- Financial barriers limit access to genetic testing, particularly for underserved populations.
Purpose of the Study:
- To evaluate the relationship between socioeconomic status and interest in hereditary cancer genetic testing.
- To identify demographic and SES predictors of genetic testing interest.
- To explore disparities in interest based on testing cost.
Main Methods:
- Utilized baseline survey data from the Early Detection of Genetic Risk (EDGE) Study (n = 2329).
- Analyzed overall interest and interest in free/low-cost genetic testing.
- Controlled for healthcare system, age, and gender in statistical models.
Main Results:
- Higher education and household income were associated with greater general interest in genetic testing.
- Lower MacArthur Subjective Social Scale (SSS) scores correlated with increased interest in free or low-cost testing.
- Education, income, and SSS emerged as significant predictors of testing interest.
Conclusions:
- Socioeconomic factors significantly influence interest in hereditary cancer genetic testing.
- Targeted strategies are needed to improve access and uptake of genetic testing among low-SES individuals.
- Ensuring equitable access to genetic testing is crucial for cancer prevention in underserved populations.
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