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Updated: Sep 21, 2025

Microfluidic Tools for Probing Fungal-Microbial Interactions at the Cellular Level
Published on: June 23, 2022
Systems Biology in Fungal Research
1Department of Molecular and Cellular Biology, University of Guelph, Guelph, ON N1G 2W1, Canada.
Abstract:
The beauty within biological systems can be uncovered using a variety of advanced technological platforms for in-depth profiling. Improvements in genome, transcriptome, proteome, and metabolome investigations, as well as data integration, are moving our understanding of diverse biological systems forward at a rapid rate. Combined with publicly available and customizable bioinformatics tools, we comprehensively profile biological changes under a plethora of circumstances. For fungal pathogens innovation is driven by our ability to explore mechanisms of antifungal resistance, reveal new relationships and interactions between a host and pathogen, improve our characterization of virulence determinants, and discover new antifungal targets. In this Special Issue dedicated to "Systems biology in fungal research", we explore each of these factors and more, highlighting the multitude of avenues and strategies available to study fungal pathogens and how they impact our environment.
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