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Pulmonary Coccidioidomycosis: A Case Report and Literature Review
Tadas Alčauskas1, Birutė Zablockienė2, Rolandas Zablockis3
1Vilnius University Faculty of Medicine, Vilnius University, M.K. Ciurlionio 21, LT-03101 Vilnius, Lithuania.
Abstract:
Coccidioidomycosis is an infectious disease caused by Coccidioides immitis or C. posadasii fungus. Humans usually get infected by inhaling spores risen from the soil. Although in 60 percent of cases symptoms are absent, remaining patients can develop various manifestations of the disease, from flu-like symptoms to severe dissemination or meningitis. In endemic regions (California, Arizona, Mexico, Central, and South America), pulmonary coccidioidomycosis causes 25% of community-acquired cases of pneumonia. We present the first registered case of pulmonary coccidioidomycosis in Lithuania. Clinical presentation, pathogenesis, treatment options, and diagnostic alternatives are discussed.
Insights
Coccidioidomycosis, a fungal infection, is reported for the first time in Lithuania. This case highlights the disease
Area of Science:
- Medical Mycology
- Infectious Diseases
- Pulmonology
Background:
- Coccidioidomycosis is a fungal infection caused by *Coccidioides* species.
- It is endemic in parts of North and South America.
- Infection occurs through inhalation of fungal spores from soil.
Observation:
- The study details the first documented case of pulmonary coccidioidomycosis in Lithuania.
- The patient presented with symptoms of this fungal pneumonia.
- The case occurred outside of the typical endemic geographical regions.
Findings:
- Pulmonary coccidioidomycosis can occur in non-endemic areas.
- Clinical presentation can range from asymptomatic to severe disseminated disease.
- Early diagnosis and treatment are crucial for patient outcomes.
Implications:
- This case expands the known geographical distribution of coccidioidomycosis.
- It underscores the importance of considering fungal infections in pneumonia, even in non-endemic regions.
- Further surveillance and awareness are needed to detect and manage coccidioidomycosis globally.
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