Related Experiment Video
Updated: Sep 21, 2025

Automated Analysis of Intracellular Phenotypes of Salmonella Using ImageJ
Published on: August 9, 2022
Through the Looking Glass: Genome, Phenome, and Interactome of Salmonella enterica
1U. S. Department of Agriculture, Agricultural Research Service, U. S. National Poultry Research Center, 950 College Station Road, Athens, GA 30605, USA.
Abstract:
This review revisits previous concepts on biological phenomenon contributing to the success of the Salmonella enterica subspecies I as a pathogen and expands upon them to include progress in epidemiology based on whole genome sequencing (WGS). Discussion goes beyond epidemiological uses of WGS to consider how phenotype, which is the biological character of an organism, can be correlated with its genotype to develop a knowledge of the interactome. Deciphering genome interactions with proteins, the impact of metabolic flux, epigenetic modifications, and other complex biochemical processes will lead to new therapeutics, control measures, environmental remediations, and improved design of vaccines.
Related Concept Videos
Stringent Response in E. coli
Global Regulatory Systems
Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Modern Molecular Taxonomy
Coordination of Gene Expression Processes in Bacteria
Genomics

