Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Preparation and Reactions of Thiols02:33

Preparation and Reactions of Thiols

6.7K
Thiols are prepared using the hydrosulfide anion as a nucleophile in a nucleophilic substitution reaction with alkyl halides. For instance, bromobutane reacts with sodium hydrosulfide to give butanethiol.
6.7K
Preparation and Reactions of Sulfides02:26

Preparation and Reactions of Sulfides

5.2K
Sulfides are the sulfur analog of ethers, just as thiols are the sulfur analog of alcohol. Like ethers, sulfides also consist of two hydrocarbon groups bonded to the central sulfur atom. Depending upon the type of groups present, sulfides can be symmetrical or asymmetrical. Symmetrical sulfides can be prepared via an SN2 reaction between 2 equivalents of an alkyl halide and one equivalent of sodium sulfide.
5.2K
Olefin Metathesis Polymerization: Overview01:13

Olefin Metathesis Polymerization: Overview

2.3K
Recently, the development of olefin metathesis polymerization advanced the field of polymer synthesis. Simply put, the reorganization of substituents on their double bonds between two olefins in the presence of a catalyst is known as the olefin metathesis reaction. The use of metathesis reaction for polymer synthesis is called olefin metathesis polymerization.
Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists...
2.3K
Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)00:53

Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)

2.0K
Acyclic diene metathesis polymerization or ADMET polymerization involves cross-metathesis of terminal dienes, such as 1,8-nonadiene, to give linear unsaturated polymer and ethylene. As ADMET is a reversible process, the formed ethylene gas must be removed from the reaction mixture to complete the polymerization process.
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Molecular epidemiology of respiratory syncytial virus in Switzerland 2019-2024 from nucleic acid testing and whole-genome sequencing.

Swiss medical weekly·2025
Same author

Loss of FXR or Bile Acid-dependent Inhibition Accelerate Carcinogenesis of Gastroesophageal Adenocarcinoma.

Cellular and molecular gastroenterology and hepatology·2025
Same author

Isolation, Characterization, and Unlocking the Potential of Mimir124 Phage for Personalized Treatment of Difficult, Multidrug-Resistant Uropathogenic <i>E. coli</i> Strain.

International journal of molecular sciences·2024
Same author

Development of Cellulose Microfibers from Mixed Solutions of PAN-Cellulose in N-Methylmorpholine-N-Oxide.

Polymers·2024
Same author

Microbiota metabolized Bile Acids accelerate Gastroesophageal Adenocarcinoma via FXR inhibition.

bioRxiv : the preprint server for biology·2024
Same author

Fully Aromatic Thermotropic Copolyesters Based on Vanillic, Hydroxybenzoic, and Hydroxybiphenylcarboxylic Acids.

Polymers·2024

Related Experiment Video

Updated: Sep 21, 2025

Synthesis of Programmable Main-chain Liquid-crystalline Elastomers Using a Two-stage Thiol-acrylate Reaction
11:17

Synthesis of Programmable Main-chain Liquid-crystalline Elastomers Using a Two-stage Thiol-acrylate Reaction

Published on: January 19, 2016

22.1K

Off-Stoichiometry Thiol-Enes Polymers Containing Silane Groups for Advanced Packaging Technologies.

Kirill Puchnin1,2, Dmitriy Ryazantsev1,2, Vitaliy Grudtsov1,2

  • 1Scientific-Manufacturing Complex "Technological Centre", Zelenograd 124498, Russia.

Polymers
|May 28, 2022
PubMed
Summary

New off-stoichiometry thiol-ene polymers (OSTE-MS) incorporate mercaptosilane for direct silicon wafer bonding. This innovation enables the creation of 3D polymer structures and microfluidic systems on chips without adhesives.

Keywords:
OSTEbondingintegrationmicrofluidicpackagingphotocuringsilanethiol–ene

More Related Videos

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers
10:09

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers

Published on: June 30, 2018

8.4K
Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
11:49

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Published on: March 8, 2019

12.8K

Related Experiment Videos

Last Updated: Sep 21, 2025

Synthesis of Programmable Main-chain Liquid-crystalline Elastomers Using a Two-stage Thiol-acrylate Reaction
11:17

Synthesis of Programmable Main-chain Liquid-crystalline Elastomers Using a Two-stage Thiol-acrylate Reaction

Published on: January 19, 2016

22.1K
Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers
10:09

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers

Published on: June 30, 2018

8.4K
Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
11:49

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Published on: March 8, 2019

12.8K

Area of Science:

  • Polymer Chemistry
  • Materials Science
  • Microfluidics

Background:

  • Off-stoichiometry thiol-ene (OSTE) polymers are versatile materials for microfabrication.
  • Direct bonding of polymers to silicon wafers typically requires surface modification or adhesives.

Purpose of the Study:

  • To develop a novel OSTE polymer (OSTE-MS) functionalized with silane groups for direct adhesion to silicon wafers.
  • To optimize the composition of OSTE-MS for 3D microfabrication on silicon chips.
  • To characterize the material properties of the developed OSTE-MS polymer.

Main Methods:

  • Introduction of mercaptosilane into the OSTE polymer mixture.
  • Determination of the optimal monomer ratio (6:6:1 allyl monomer:mercapto monomer:mercaptosilane).
  • Comprehensive material characterization including mechanical, thermal, optical, and chemical resistance tests.

Main Results:

  • OSTE-MS polymers exhibit inherent adhesion to silicon wafers without surface pre-treatment.
  • The optimal composition allows for the fabrication of stable 3D polymer structures.
  • Characterization confirmed desirable properties such as hardness, tensile strength, optical transparency, and thermal stability.

Conclusions:

  • The developed OSTE-MS polymers offer a facile method for fabricating 3D structures and microfluidic devices directly on silicon.
  • The silane functionalization eliminates the need for adhesives, simplifying device fabrication processes.
  • OSTE-MS polymers represent a promising material for advanced micro- and nanofluidic applications.