One-Pot Synthesis of SnO₂-rGO Nanocomposite for Enhanced Photocatalytic and Anticancer Activity

Metal oxide and graphene derivative-based nanocomposites (NCs) are attractive to the fields of environmental remediation, optics, and cancer therapy owing to their remarkable physicochemical characteristics. There is limited information on the environmental and biomedical applications of tin oxide-reduced graphene oxide nanocomposites (SnO₂-rGO NCs). The goal of this work was to explore the photocatalytic activity and anticancer efficacy of SnO₂-rGO NCs. Pure SnO₂ NPs and SnO₂-rGO NCs were prepared using the one-pot hydrothermal method. X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared (FTIR), UV-Vis spectrometry, photoluminescence (PL), and Raman scattering microscopy were applied to characterize the synthesized samples. The crystallite size of the SnO₂ NPs slightly increased after rGO doping. TEM and SEM images show that the SnO₂ NPs were tightly anchored onto the rGO sheets. The XPS and EDX data confirmed the chemical state and elemental composition of the SnO₂-rGO NCs. Optical data suggest that the bandgap energy of the SnO₂-rGO NCs was slightly lower than for the pure SnO₂ NPs. In comparison to pure SnO₂ NPs, the intensity of the PL spectra of the SnO₂-rGO NCs was lower, indicating the decrement of the recombination rate of the surfaces charges (e^-/h⁺) after rGO doping. Hence, the degradation efficiency of methylene blue (MB) dye by SnO₂-rGO NCs (93%) was almost 2-fold higher than for pure SnO₂ NPs (54%). The anticancer efficacy of SnO₂-rGO NCs was also almost 1.5-fold higher against human liver cancer (HepG2) and human lung cancer (A549) cells compared to the SnO₂ NPs. This study suggests a unique method to improve the photocatalytic activity and anticancer efficacy of SnO₂ NPs by fusion with graphene derivatives.