Related Experiment Video

Updated: Sep 21, 2025

Investigating the Protective Effects of Platycodin D on Non-Alcoholic Fatty Liver Disease in a Palmitic Acid-Induced In Vitro Model
08:20

Investigating the Protective Effects of Platycodin D on Non-Alcoholic Fatty Liver Disease in a Palmitic Acid-Induced In Vitro Model

Published on: December 2, 2022

2.0K

Gut-specific inhibition of PPARα as a novel approach of NAFLD treatment

Lanjing Zhang1,2,3, Grace L Guo4,5

  • 1Department of Pathology , Princeton Medical Center , Plainsboro , New Jersey , USA.

Hepatology (Baltimore, Md.)
|May 28, 2022
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis
08:58

Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis

Published on: March 11, 2017

16.1K
Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss
07:03

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss

Published on: July 19, 2024

1.1K

Related Experiment Videos

Last Updated: Sep 21, 2025

Investigating the Protective Effects of Platycodin D on Non-Alcoholic Fatty Liver Disease in a Palmitic Acid-Induced In Vitro Model
08:20

Investigating the Protective Effects of Platycodin D on Non-Alcoholic Fatty Liver Disease in a Palmitic Acid-Induced In Vitro Model

Published on: December 2, 2022

2.0K
Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis
08:58

Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis

Published on: March 11, 2017

16.1K
Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss
07:03

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss

Published on: July 19, 2024

1.1K

Related Concept Videos

Transducer Mechanism: Nuclear Receptors01:31

Transducer Mechanism: Nuclear Receptors

1.7K
Nuclear receptors, or NRs, are unique transcription factors that regulate gene transcription and affect the cellular pathways involved in reproduction, development, or metabolism. Their ability to be stimulated by small lipophilic ligands and control vital cellular processes makes them ideal drug targets. Nearly 10-15% of currently prescribed drugs target these receptors.
About 48 different soluble family members of nuclear receptors are identified that can be divided into two main classes:
1.7K

Articles linked to this work by shared authors, journal, and citation graph.

Persistent activation of growth hormone contributes to sexual dimorphic expression of hepatic drug metabolizing enzymes in Fgf15 transgenic mice.

Drug metabolism and disposition: the biological fate of chemicals·2026

Mutation of PXR phosphorylation motif at Ser347 disrupts lipid and bile acid homeostasis in diet-induced metabolic dysfunction-associated steatohepatitis in mice.

Drug metabolism and disposition: the biological fate of chemicals·2026

Ursodeoxycholic acid acts as an ileal FXR agonist in male mice with hepatic deficiency of FXR.

eGastroenterology·2025

Dual Effects of Maternal Diet and Perinatal Organophosphate Flame Retardant Treatment on Offspring Development, Behavior and Metabolism.

Toxics·2025

Fibroblast growth factor 15 overexpression and combined peroxisome proliferator-activated receptor α activation attenuates metabolic dysfunction-associated steatohepatitis progression in mice.

Drug metabolism and disposition: the biological fate of chemicals·2025

Deletion of hepatic FXR leads to more severe MASH development in female mice.

Hepatology communications·2025

Saroglitazar improves hepatic steatosis and liver enzymes in women with polycystic ovary syndrome and MASLD: A multicenter, double-blind, placebo-controlled study.

Hepatology (Baltimore, Md.)·2026

Upholding telomeres prevents hepatic stellate cell transdifferentiation and liver fibrogenesis.

Hepatology (Baltimore, Md.)·2026

Autoimmune hepatitis and primary biliary cholangitis are among a subset of autoimmune diseases defined by profound co-prevalence and genetic risk association with the IL12 pathway.

Hepatology (Baltimore, Md.)·2026

Adjuvant pegylated interferon-alpha after nucleos(t)ide analog withdrawal drives a temporally coordinated expansion of regulatory B cells and contraction of HBV-specific T cells.

Hepatology (Baltimore, Md.)·2026

An international multicenter analysis of the outcome of pediatric first variceal hemorrhage.

Hepatology (Baltimore, Md.)·2026

AASLD EXPO: Liver biopsy.

Hepatology (Baltimore, Md.)·2026

Resource-efficient use of industrial residue for multifunctional cacao nanofibers.

Frontiers in bioengineering and biotechnology·2026

Construction of electrostatic binding V-type starches using cationic starch and lauric acid: Insight into enhanced digestive resistance.

Food chemistry: X·2026

Mechanistic benchmarking of SNAC, DDM, and LLC reveals enhancer-dependent pathways for intestinal semaglutide delivery.

Journal of controlled release : official journal of the Controlled Release Society·2026

Increase in 6-pentyl-alpha-pyrone production by Trichoderma spp. in liquid medium using in situ removal by adsorbent resin.

Natural products and bioprospecting·2026

Integrated genetic and process engineering of Pichia pastoris for high-yield ergothioneine production via methanol-free cultivation.

Bioresource technology·2026

Interfacial engineering of zein nanoparticles by phosphatidylcholine and polysaccharide synergy: Enhanced quercetin delivery and improved ultrasonic emulsification stability.

Food chemistry·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us