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PECULIARITIES OF THYROID STATUS OF PRESCHOOL CHILDREN WITH ACUTE BRONCHITIS

Oleksandr Smiyan1, Anastasiia Havrylenko1, Andriy Loboda1

  • 1SUMY STATE UNIVERSITY, SUMY, UKRAINE.

Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|May 28, 2022
PubMed

Insights

Thyroid hormone abnormalities, including euthyroid sick syndrome, are common in preschool children with acute bronchitis. These functional shifts affect thyroid hormone levels, impacting overall health status.

Area of Science:

  • Pediatric Endocrinology
  • Infectious Diseases

Background:

  • Acute bronchitis is a common respiratory illness in preschool children.
  • Thyroid function can be affected by systemic infections.

Purpose of the Study:

  • To investigate thyroid status in preschool children diagnosed with acute bronchitis.
  • To characterize thyroid hormone levels, including total and free triiodothyronine and thyroxine, and antibodies to thyroperoxidase.

Main Methods:

  • A cohort of 135 preschool children (3-6 years) with acute bronchitis was studied.
  • A control group of 28 healthy children was included for comparison.
  • Clinical, laboratory, and instrumental methods were employed, with statistical analysis using SPSS 26.

Main Results:

  • Subclinical thyroid abnormalities were observed in 33% of children with acute bronchitis, presenting as euthyroid sick syndrome.
  • Elevated serum reversible triiodothyronine and decreased total and free triiodothyronine were noted.
  • No specific mention of antibodies to thyroperoxidase results in the abstract.

Conclusions:

  • Functional shifts in hormonal status, consistent with euthyroid sick syndrome, occur in nearly one-third of preschool children with acute bronchitis.
  • These findings highlight the potential impact of acute bronchitis on thyroid function in young children.
Abstract

Keywords:
acute bronchitischildreneuthyroid sick syndromethyroxinetriiodothyronine

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