Tea consumption and cerebral hemorrhage risk: a meta-analysis

Area of Science:

• Cardiovascular Health
• Nutritional Epidemiology
• Preventive Medicine

Background:

• Tea possesses bioactive polyphenols with antithrombotic and antioxidant properties.
• Previous studies on tea consumption and cerebral hemorrhage risk have yielded inconsistent findings.
• A comprehensive meta-analysis is needed to clarify the association.

Purpose of the Study:

• To systematically evaluate the relationship between tea consumption and the risk of cerebral hemorrhage.
• To synthesize evidence from observational studies to provide a clearer understanding of this association.

Main Methods:

• A systematic literature search was conducted across major databases (Web of Science, PubMed, Embase, Scopus) up to December 2021.
• Relative risks (RRs) and odds ratios (ORs) were extracted from eligible observational studies.
• Meta-analysis techniques were employed to synthesize the data.

Main Results:

• Ten studies comprising over 721,827 participants were analyzed.
• Higher tea consumption was associated with a 23% reduced risk of cerebral hemorrhage (RR = 0.77).
• Green tea, and adjustments for alcohol, diet, and physical activity showed significant preventive effects. Each daily cup correlated with a 2-6% risk reduction.

Conclusions:

• Daily tea intake is associated with a lower risk of cerebral hemorrhage in adults.
• Green tea consumption demonstrates a more pronounced protective effect.
• Future research should explore the interaction between tea, physical activity, diet, and alcohol intake in relation to hemorrhagic stroke.