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Isolation of a new steroid from phytochemical investigation on Caralluma lasiantha
Malladi Sireesha1, Venkata Nadh Ratnakaram2, Kothamasu Suresh Babu3
1Division of Chemistry, Department of Science and Humanities, Vignan's Foundation for Science, Technology and Research (Deemed to be University), Vadlamudi, Guntur, Andhra Pradesh 522213, India.
Abstract:
A new steroid (acylated C21 pregnane steroid) was isolated from chloroform extract in phytochemical screening of Caralluma lasiantha. The isolated compound is found to be 3β-hydroxy-14β-(6'- carboxyphenyl)propionyloxypregn-5-en-20-one based on spectroscopic studies (IR, 1H NMR, 13C NMR, DEPT, COSY, HSQC, HMBC and ESI-MS). The isolated new steroid was tested against four bacterial strains and the activity was related to the structure of the molecule.
