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Sexual Dysfunction in Infertile Men: A Systematic Review and Meta-Analysis
Yang Liu1, Yuning Wang1, Zhuonan Pu1
1College of Clinical Medical Sciences, Dalian Medical University, Dalian, China.
Infertile men experience a higher prevalence of sexual dysfunction, impacting erectile function, orgasm, and desire. This meta-analysis confirms a significant association between male infertility and sexual health issues.
Area of Science:
- Reproductive Medicine
- Men's Health
- Sexual Medicine
Background:
- The link between male infertility and sexual dysfunction is infrequently studied and debated.
- Previous research has yielded controversial findings regarding this association.
Purpose of the Study:
- To conduct a meta-analysis evaluating the prevalence of sexual dysfunction in infertile men.
- To assess the International Index of Erectile Function (IIEF) scores among infertile males.
Main Methods:
- Systematic literature search across PubMed, EMBASE, and Cochrane Library.
- Meta-analysis of 8 controlled studies using Odds Ratio (OR) for morbidity and Standardized Mean Differences (SMD) for IIEF scores.
- Data analyzed using Review Manager 5.4 software.
Main Results:
- Infertile men exhibited a significantly higher prevalence of sexual dysfunction compared to controls (OR = 2.66).
- Infertile men reported lower IIEF scores, indicating poorer erectile function (SMD = -0.47).
- Erectile function, orgasm, and sexual desire were the most affected aspects of sexual function.
Conclusions:
- Male infertility is significantly associated with an increased prevalence of sexual dysfunction.
- Further research with rigorous designs is recommended to explore this association.
- This systematic review is the first to consolidate data on sexual dysfunction prevalence and severity in male infertility.
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