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Residue-specific Incorporation of Noncanonical Amino Acids into Model Proteins Using an Escherichia coli Cell-free Transcription-translation System
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The pathogenesis of, and pharmacological treatment for, Canavan disease

Huijun Wei1, John R Moffett2, Man Amanat3

  • 1Johns Hopkins Drug Discovery, Johns Hopkins University School of Medicine, 855 N. Wolfe Street, Baltimore, MD 21205, USA; Department of Neurology, Johns Hopkins University School of Medicine, 855 N. Wolfe Street, Baltimore, MD 21205, USA; Department of Pharmacology and Molecular Science, Johns Hopkins University School of Medicine, 855 N. Wolfe Street, Baltimore, MD 21205, USA.

Drug Discovery Today
|May 31, 2022
PubMed

Keywords:
Aspartate N-acetyltransferase (Asp-NAT)Aspartoacylase (ASPA)Canavan disease (CD)N-acetylaspartate (NAA)NaDC3

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