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COVID-19 in the Immunocompromised Host, Including People with Human Immunodeficiency Virus
Niyati Jakharia1, Aruna K Subramanian1, Adrienne E Shapiro2
1Department of Medicine, Division of Infectious Disease, Stanford University School of Medicine, 300 Pasteur Drive, Lane L134, Stanford, CA 94305, USA.
Abstract:
This review describes the incidence, epidemiology, and risk factors for mortality of COVID-19 in immunocompromised patients, including persons with human immunodeficiency virus. It describes various preventive measures, including vaccines and their effectiveness and the role of monoclonal antibodies for pre-exposure prophylaxis. It also reviews the different treatment options for immunocompromised individuals, including antivirals, monoclonal antibodies, and immunomodulators. Lastly, it describes the impact of COVID-19 on transplantation and continuity care of this population.
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